Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG2b) to Human CREBBP / CREB Binding Protein
Human, Monkey, Mouse, Rat
IHC - Paraffin, Immunofluorescence
Mouse Monoclonal [clone NM11] (IgG2b,k)
Monkey, Mouse, Rat, Mink
CREBBP / CREB Binding Protein
Monkey, Mouse, Rat, Mink (tested or 100% immunogen sequence identity)
IgG2b,k Monoclonal [NM11]
Specificity and Use
E1A affinity purified p300 protein.
stains with a 300 kD protein. P300 and CBP (CREB-binding protein) are homologous to each other. P300 is transcriptional adapter protein, which is characterized by three cysteine and histidine-rich regions. Protein kinase A mediated CREB phosphorylation results in the binding of CREB to a 265 kD nuclear protein designated CBP. This antibody cross reacts with monkey, mink, mouse and rat.
CREBBP Antibody, CREB binding protein Antibody, CREB-binding protein Antibody, KAT3A Antibody, RSTS Antibody, Rubinstein-Taybi syndrome Antibody, RTS Antibody, CBP Antibody
CREBBP / CREB Binding Protein is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition.