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Anti-CREB1 / CREB Antibody (phospho-Ser133) LS-C22429

Ordering

Wt. Vol. Conc. Price
100 µg - - $650
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CREB1 / CREB Antibodies

Anti-CREB1 / CREB Antibody (phospho-Ser133) LS-C248
Rabbit Polyclonal to Rat CREB1 / CREB
Rat, Human, Mouse, Bovine, Dog, Chicken, Xenopus
Western blot
Unconjugated
Western blot Image
Anti-CREB1 / CREB Antibody (aa251-300) LS-C110441
Rabbit Polyclonal to Human CREB1 / CREB
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Western blot
Unconjugated
Western blot Image
Anti-CREB1 / CREB Antibody (clone 5G3) LS-C169350
Mouse Monoclonal [clone 5G3] (IgG1) to Human CREB1 / CREB
Human, Monkey, Mouse, Rat
IHC - Paraffin, ICC, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1,k) to Human CREB1 / CREB
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human CREB1 / CREB
Mouse
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Unconjugated
Gel filtration
Unmodified

Applications

Western blot (0.5 - 2 µg/ml)

Specificity and Use

CREB1 / CREB antibody was raised against kLH-conjugated, synthetic peptide (REILSRRP(pS)YR) corresponding to amino acids 125-135 of human CREB. The immunizing sequence is identical in human and mouse.
pSer133
Recognizes phosphorylated CREB at 46kD. May also recognize p30 and p38 proteins, which likely correspond to phosphorylated CREM and ATF-1 respectively, since the two proteins share significant homology with the phosphorylated CREB immunizing peptide. Species cross-reactivity: Human and mouse. Rat Cross-reactivity predicted based on sequence homology.
Suitable for use in Western Blot. Western Blot: 0.5-2 ug/ml.

Packaging

Supplied as frozen serum-free cell culture supernatant in 30ul of 2X PBS containing PEG 3000, sucrose, and 0.09% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About CREB1 / CREB

P16220 NM_134442 NP_004370.1

CREB1 Antibody, CREB-1 Antibody, Transactivator protein Antibody, CREB Antibody

CREB (cAMP response element binding protein1), a DNA binding protein, is a member of the leucine zipper family of transcription factors. CREB interaction with DNA requires phosphorylation at Ser 119 by activated cAMP protein kinase A. Once phosphorylated CREB binds to an 8 base enhancer know as the cAMP response element (CRE) containing a conserved core sequence TGACG. CREB also interacts with CBP (CREB binding protein) and RNA polymerase II when phosphorylated on Ser 133.

Requested From: United States
Date Requested: 12/7/2016

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