CR1 / CD35

complement component (3b/4b) receptor 1 (Knops blood group)

CR1 / CD35 is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.

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Products

Antibodies (90)

ELISA Kits (6)

Proteins (2)

Type

Primary (90)

Recombinant (2)

Sandwich (5)

Sandwich CLIA (1)

Target

CR1 / CD35 (98)

Reactivity

Human (93)

Mouse (3)

Baboon (3)

Cynomolgus (1)

Cynomolgus monkey (2)

Monkey (11)

Non-Human Primates (3)

Rhesus monkey (2)

Application

IHC (42)

IHC-Fr (25)

IHC-P (32)

WB (46)

Flo (60)

ELISA (13)

ICC (7)

IF (10)

IP (17)

Peptide-ELISA (1)

Host

rabbit (23)

mouse (65)

rabbit-new zealand white (1)

rat (1)

Product Group

IHCPlus (1)

PathPlus Cancer (3)

PathPlus Cancer Pathology (3)

Isotype

IgG (13)

IgG,k (1)

IgG1 (41)

IgG1,k (18)

IgG2a,k (1)

IgG2b (4)

Clonality

monoclonal mc (65)

polyclonal pc (23)

recombinant monoclonal rmc (2)

Clone

31R (1)

5H3/B1 (1)

8C12 (2)

AR2 (3)

CR1/802 (3)

E11 (26)

KT23 (1)

OTI2A8 (2)

RLB25 (2)

SPM554 (2)

To5 (5)

TS106 (1)

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Format

12 x 8-Well Microstrips (2)

96-Well Microplate (1)

96-Well Strip Plate (3)

AF488 Conjugated (1)

AF647 Conjugated (1)

APC (1)

APC Conjugated (4)

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Cy7 Conjugated (2)

FITC Conjugated (12)

HRP Conjugated (3)

PE (2)

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Preservative Free (1)

Ready-to-Use (3)

RPE Conjugated (2)

Unconjugated (47)

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Epitope

aa1780-2039 (8)

aa420-550 (3)

CD35 (complement receptor 1) (2)

aa1900-2039 (2)

aa1990-2038 (1)

aa42-1971 (1)

aa901-1095 (1)

aa989-2011 (1)

Publications

No (96)

Yes (2)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (5)

Serum (5)

Tissue Homogenates (2)

Tag

GST, N-terminus (1)

His, N-Terminal (1)

Species

Human (2)

Source

E. coli (2)

Purification

Purified (1)

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IHC-plus™ CR1 / CD35 Antibody (clone E11, Preservative Free) LS-B2556

(4.0) Rating

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (Preservative Free) (E11) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P

Format:

Unconjugated, Preservative Free

Price:

50 µg/$555

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CR1 / CD35 Antibody (aa420-550) LS-C675585

(4.0) Rating

(1) Publication(s)

Antibody:

CR1 / CD35 Rabbit anti-Human Polyclonal (aa420-550) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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CR1 / CD35 Antibody (Biotin) LS-C35559

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Flo, IHC

Format:

Biotin Conjugated

Price:

100 µg/$626

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CR1 / CD35 Antibody (clone RLB25) LS-C311982

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (RLB25) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$327

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CR1 / CD35 Antibody (clone 31R, Concentrated) LS-C146592

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (Concentrated) (31R) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated, Concentrated

Price:

100 µg/$765

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Human CR1 / CD35 (Sandwich ELISA) ELISA Kit - LS-F6321

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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CR1 / CD35 Antibody (CD35 (complement receptor 1), clone 8C12) LS-C777464

(4.0) Rating

(1) Publication(s)

Antibody:

CR1 / CD35 Rabbit anti-Mouse Recombinant Monoclonal (CD35 (complement receptor 1)) (8C12) Antibody

Reactivity:

Mouse

Applications:

Flo, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

0.2 mg/$540

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CR1 / CD35 Antibody (clone E11, Biotin) LS-C134401

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (Biotin) (E11) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Biotin Conjugated

Price:

100 µg/$446

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CR1 / CD35 Antibody (clone 5H3/B1) LS-C88946

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (5H3/B1 ) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

200 µg/$649

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PathPlus™ CR1 / CD35 Antibody (clone E11) LS-B7301

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (E11) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$440

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CR1 / CD35 Antibody LS-C121517

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human, Monkey, Baboon, Cynomolgus

Applications:

Flo, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$597; 200 µg/$807

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CR1 / CD35 Antibody (Biotin) LS-C524276

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human, Monkey

Applications:

Flo, IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$860

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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Human CR1 / CD35 (Sandwich ELISA) ELISA Kit - LS-F49874

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.2 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$672

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Human CR1 / CD35 Protein (Recombinant His, N-Terminal) (Ile1780-Pro2039) - LS-G13373

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

30.4 kDa

Price:

10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866

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CR1 / CD35 Antibody (FITC) LS-C4989

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P, IP, WB

Format:

FITC Conjugated

Price:

100 Tests/$508

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CR1 / CD35 Antibody (clone E11, APC) LS-C751041

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (APC) (E11) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IHC-Fr, IHC-P, IP, WB

Format:

APC Conjugated

Price:

100 Tests/$365

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CR1 / CD35 Antibody (clone E11, FITC) LS-C351622

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (FITC) (E11) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P

Format:

FITC Conjugated

Price:

100 Tests/$367

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CR1 / CD35 Antibody (aa901-1095) LS-C677590

Antibody:

CR1 / CD35 Rabbit anti-Human Polyclonal (aa901-1095) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

PathPlus™ CR1 / CD35 Antibody LS-B16130

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$460

Select

CR1 / CD35 Antibody LS-C813296

Antibody:

CR1 / CD35 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

CR1 / CD35 Antibody (clone E11) LS-C357762

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (E11) Antibody

Reactivity:

Human, Baboon, Cynomolgus monkey, Rhesus monkey

Applications:

ELISA, Flo, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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PathPlus™ CR1 / CD35 Antibody (clone E11, Azide-free, BSA-free) LS-B16937

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (E11) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P

Format:

Unconjugated, Azide-free, BSA-free

Price:

50 µg/$460

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CR1 / CD35 Antibody (clone E11, Ready-to-Use) LS-C389530

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (Ready-to-Use) (E11) Antibody

Reactivity:

Human, Baboon, Cynomolgus monkey, Rhesus monkey

Applications:

ELISA, Flo, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

Select

CR1 / CD35 Antibody LS-C4991

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human, Monkey

Applications:

Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

500 µl/$836

Select

CR1 / CD35 Antibody (clone To5) LS-C348208

Antibody:

CR1 / CD35 Mouse anti-Human Monoclonal (To5) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

200 µg/$480

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