CPSF3 / CPSF

cleavage and polyadenylation specific factor 3, 73kDa

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity, and functions as mRNA 3'-end-processing endonuclease. Also involved in the histone 3'-end pre-mRNA processing. U7 snRNP-dependent protein that induces both the 3'-endoribonucleolytic cleavage of histone pre-mRNAs and acts as a 5' to 3' exonuclease for degrading the subsequent downstream cleavage product (DCP) of mature histone mRNAs. Cleavage occurs after the 5'-ACCCA-3' sequence in the histone pre-mRNA leaving a 3'hydroxyl group on the upstream fragment containing the stem loop (SL) and 5' phosphate on the downstream cleavage product (DCP) starting with CU nucleotides. The U7-dependent 5' to 3' exonuclease activity is processive and degrades the DCP RNA substrate even after complete removal of the U7-binding site. Binds to the downstream cleavage product (DCP) of histone pre-mRNAs and the cleaved DCP RNA substrate in a U7 snRNP dependent manner.

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Products

Antibodies (28)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (28)

Recombinant (3)

Target

CPSF3 / CPSF (33)

Reactivity

Human (28)

Mouse (8)

Rat (7)

Bat (3)

Bovine (3)

Chicken (3)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Guinea pig (3)

Horse (3)

Monkey (6)

Orangutan (6)

Pig (3)

Rabbit (6)

Xenopus (3)

Zebrafish (3)

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Application

IHC (7)

IHC-P (7)

WB (27)

ELISA (8)

IF (1)

IP (1)

Host

rabbit (26)

mouse (2)

Product Group

IHCPlus (2)

Isotype

IgG (26)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (27)

Clone

1H8 (1)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (12)

Epitope

aa192-221 (7)

C-Terminus (4)

aa189-238 (4)

aa634-684 (2)

aa1-50 (1)

Publications

No (33)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

CPSF3 / CPSF Antibody (clone 1H8) LS-C139136

Antibody:

CPSF3 / CPSF Mouse anti-Human Monoclonal (1H8) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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CPSF3 / CPSF Antibody (aa189-238) LS-C31377

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa189-238) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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IHC-plus™ CPSF3 / CPSF Antibody (aa634-684) LS-B11044

(4.0) Rating

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa634-684) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$460

Select

IHC-plus™ CPSF3 / CPSF Antibody (aa1-50) LS-B12211

(4.0) Rating

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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CPSF3 / CPSF Antibody (aa634-684) LS-C287919

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa634-684) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

CPSF3 / CPSF Antibody (C-Terminus) LS-C31378

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

Select

CPSF3 / CPSF Antibody (C-Terminus, HRP) LS-C441172

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rat, Rabbit, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

CPSF3 / CPSF Antibody (C-Terminus, Biotin) LS-C441170

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rat, Rabbit, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

CPSF3 / CPSF Antibody (C-Terminus, FITC) LS-C441171

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rat, Rabbit, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CPSF3 / CPSF Antibody LS-C664769

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

CPSF3 / CPSF Antibody (aa192-221) LS-C320568

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa192-221) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

CPSF3 / CPSF Antibody (aa192-221, Biotin) LS-C234181

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa192-221) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

CPSF3 / CPSF Antibody (aa192-221, FITC) LS-C234182

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa192-221) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

CPSF3 / CPSF Antibody (aa192-221, Azide-free, HRP) LS-C249743

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa192-221) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

CPSF3 / CPSF Antibody (aa192-221, APC) LS-C234180

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa192-221) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

CPSF3 / CPSF Antibody (aa192-221, PE) LS-C234187

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa192-221) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

CPSF3 / CPSF Antibody LS-C307076

Antibody:

CPSF3 / CPSF Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

CPSF3 / CPSF Antibody LS-C309980

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

CPSF3 / CPSF Antibody (HRP) LS-C541593

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

CPSF3 / CPSF Antibody (Biotin) LS-C521463

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

CPSF3 / CPSF Antibody (FITC) LS-C531506

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

CPSF3 / CPSF Antibody (PE) LS-C649705

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

Select

CPSF3 / CPSF Antibody (APC) LS-C513247

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

CPSF3 / CPSF Antibody LS-C747479

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

CPSF3 / CPSF Antibody (aa192-221) LS-C167003

Antibody:

CPSF3 / CPSF Rabbit anti-Human Polyclonal (aa192-221) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Viewing 1-25 of 33 product results

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