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CPE / Carboxypeptidase E

carboxypeptidase E

Carboxypeptidase E / CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.

Gene Name: carboxypeptidase E
Family/Subfamily: Exopeptidase , Metallopeptidase M14
Synonyms: CPE, Carboxypeptidase E, CPH, Carboxypeptidase H, Enkephalin convertase
Target Sequences: NM_001873 NP_001864.1 P16870

Publications (1)

1
Expression of Secretogranin III in Chicken Endocrine Cells: Its Relevance to the Secretory Granule Properties of Peptide Prohormone Processing and Bioactive Amine Content. Gomi H, Morikawa S, Shinmura N, Moki H, Yasui T, Tsukise A, Torii S, Watanabe T, Maeda Y, Hosaka M. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2015 63:350-66. (WB; Human) [Full Text Article] [PubMed:25673289] [PMC:PMC4409946] Related Antibodies: LS-B6638.

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Antibodies (43)
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CPE / Carboxypeptidase E (69)
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CPE / Carboxypeptidase E Antibody - Anti-CPE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CPE / Carboxypeptidase E Antibody - Anti-CPE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody
Xenopus, Zebrafish, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CPE / Carboxypeptidase E Antibody - Anti-CPE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody
Xenopus, Zebrafish, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CPE / Carboxypeptidase E Antibody - Anti-CPE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody
Xenopus, Zebrafish, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CPE / Carboxypeptidase E Antibody - Anti-Carboxypeptidase E / CPE antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$485
CPE / Carboxypeptidase E Antibody - Anti-Carboxypeptidase E / CPE antibody IHC staining of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa271-320) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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CPE / Carboxypeptidase E Goat anti-Human Polyclonal (aa42-453) Antibody
Human
ELISA, Flo, IP, WB
Unconjugated
100 µg/$930
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CPE / Carboxypeptidase E Mouse anti-Human Monoclonal (aa42-453) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$884
CPE / Carboxypeptidase E Antibody - Western blot of CPE antibody in mouse cerebellum tissue lysates (35 ug/lane). CPE (arrow) was detected using the purified antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa381-412) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
CPE / Carboxypeptidase E ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$834
CPE / Carboxypeptidase E Antibody - Immunohistochemistry of paraffin-embedded rat brain tissue.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CPE / Carboxypeptidase E Antibody - Staining RAW264.7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$394
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CPE / Carboxypeptidase E Antibody - Positive Western Blot detected in A375 whole cell lysate. All lanes: CPE antibody at 2.7 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 54, 50 KDa. Observed band size: 54 KDa
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
CPE / Carboxypeptidase E Antibody - Western blot analysis of lysate from mouse brain cells, using CPE Antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CPE / Carboxypeptidase E Antibody - Western blot of CPE antibody
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (421-470 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CPE / Carboxypeptidase E Antibody - Western blot analysis of extracts from 3T3 cells and RAW264.7cells, using CPE antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CPE / Carboxypeptidase E Antibody - Western blot of CPE antibody
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (240-320 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CPE / Carboxypeptidase E Antibody - Western blot analysis of the lysates from HeLa cells using CPE antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa256-305) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
CPE / Carboxypeptidase E Antibody - Western blot of recombinant Carboxypeptidase E / CPE.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa318-476) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
CPE / Carboxypeptidase E Antibody - Western blot of recombinant Carboxypeptidase E / CPE.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa318-476) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Viewing 1-25 of 69 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).