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COX6A2

cytochrome c oxidase subunit VIa polypeptide 2

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.

Gene Name: cytochrome c oxidase subunit VIa polypeptide 2
Synonyms: COX6A2, COX6A, COX6AH, COXVIAH, COX VIa-M
Target Sequences: NM_005205 NP_005196.1 Q02221

Publications (1)

1
COX6A2 variants cause a muscle-specific cytochrome c oxidase deficiency. Michio Inoue, Shumpei Uchino, Aritoshi Iida, Satoru Noguchi, Shinichiro Hayashi, Tsutomu Takahashi, Katsunori Fujii, Hirofumi Komaki, Eri Takeshita, Ikuya Nonaka, Yukinori Okada, Takuya Yoshizawa, Leentje Van Lommel, Frans Schuit, Yu-Ichi Goto, Masakazu Mimaki, Ichizo Nishino. Annals of neurology. 2019 August;86:193-202. [Full Text Article] [PubMed:31155743] Related Antibodies: LS-C166966.

☰ Filters
Antibodies (13)
Proteins (3)
Over-Expression Lysate (2)
Primary (13)
Recombinant (1)
COX6A2 (16)
Human (13)
Mouse (9)
Rat (2)
Monkey (1)
IHC (2)
IHC-P (1)
WB (12)
ELISA (10)
Peptide-ELISA (1)
rabbit (13)
IgG (11)
polyclonal pc (13)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (8)
aa37-66 (7)
aa34-97 (1)
No (15)
Yes (1)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
COX6A2 Antibody - Western blot of lysate from human skeletal muscle tissue lysate, using COX6A2 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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COX6A2 Rabbit anti-Human Polyclonal (aa37-66) Antibody
Human
WB
Unconjugated
400 µl/$393
COX6A2 Antibody - IHC of paraffin-embedded SCC4 xenograft using COX6A2 antibody at 1:100 dilution.
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COX6A2 Rabbit anti-Human Polyclonal (aa34-97) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$450
COX6A2 Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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COX6A2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
COX6A2 Rabbit anti-Human Polyclonal (aa37-66) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
COX6A2 Rabbit anti-Human Polyclonal (aa37-66) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
COX6A2 Rabbit anti-Human Polyclonal (aa37-66) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
COX6A2 Rabbit anti-Human Polyclonal (aa37-66) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
COX6A2 Rabbit anti-Human Polyclonal (aa37-66) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
COX6A2 Rabbit anti-Human Polyclonal (aa37-66) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
COX6A2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
COX6A2 Antibody - Western blot analysis of Mouse heart tissue Human heart tissue Human muscle tissue lysates  using COX6A2 Polyclonal Antibody at dilution of 1:400
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COX6A2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
COX6A2 Antibody - Western blot analysis of Human muscle tissue Human heart tissue Mouse heart tissue lysates  using COX6A2 Polyclonal Antibody at dilution of 1:450
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COX6A2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
COX6A2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$331
COX6A2 Protein - Purified recombinant protein COX6A2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
9.4 kDa
20 µg/$1,107
COX6A2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
10.82 kDa
100 µg/$494
COX6A2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
10.82 kDa
20 µg/$150
Viewing 1-16 of 16 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).