Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CORO1A Antibody, Clipin-A Antibody, Coronin-like protein A Antibody, Coronin-like protein p57 Antibody, CLIPINA Antibody, Coronin-1 Antibody, Coronin-1A Antibody, HCORO1 Antibody, p57 Antibody, TACO Antibody, CLABP Antibody, CORO1 Antibody
May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
Immunocytochemistry of a mixed neuron/glial culture from newborn rat brain stained (green) at a dilution of 1:10000 and chicken anti-vimentin antibody at 1:5000. Blue is nuclear DNA counter stain. Glial cells and fibroblasts stain with vimentin, while microglia alone stain strongly and specifically for Coronin 1a, which can therefore be used as a robust marker of this important cell type.
Coronin 1a Antibody - Western blot of HL60 Cell extract stained with RPCA-Cor1a, at dilution of 1:10,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~57kDa corresponds to Coronin 1a. Numbers represent positions of molecular weight standards in kDa.