COPS8 / COP9

COP9 signalosome subunit 8

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

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Products

Antibodies (27)

Proteins (8)

Type

Over-Expression Lysate (4)

Primary (27)

Recombinant (4)

Target

COPS8 / COP9 (35)

Reactivity

Human (27)

Mouse (7)

Rat (8)

Bovine (3)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (3)

Orangutan (3)

Rabbit (3)

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Application

IHC (3)

IHC-P (2)

WB (23)

ELISA (15)

IF (1)

Peptide-ELISA (1)

Host

rabbit (20)

mouse (7)

Product Group

IHCPlus (1)

Isotype

IgG (16)

IgG2a,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (21)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (11)

Epitope

aa1-30 (7)

C-Terminus (4)

Publications

No (35)

Tag

GST (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (2)

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IHC-plus™ COPS8 / COP9 Antibody LS-B4592

(4.0) Rating

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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COPS8 / COP9 Antibody LS-C664714

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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COPS8 / COP9 Antibody LS-C671988

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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COPS8 / COP9 Antibody (FITC) LS-C671989

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• FITC

• Unconjugated
• FITC

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COPS8 / COP9 Antibody LS-C307815

Antibody:

COPS8 / COP9 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

COPS8 / COP9 Antibody (HRP) LS-C541571

Antibody:

COPS8 / COP9 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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COPS8 / COP9 Antibody (Biotin) LS-C521439

Antibody:

COPS8 / COP9 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

COPS8 / COP9 Antibody (FITC) LS-C531483

Antibody:

COPS8 / COP9 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

COPS8 / COP9 Antibody (PE) LS-C649683

Antibody:

COPS8 / COP9 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

Select

COPS8 / COP9 Antibody (APC) LS-C513224

Antibody:

COPS8 / COP9 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

COPS8 / COP9 Antibody (aa1-30) LS-C320525

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

COPS8 / COP9 Antibody (aa1-30, Biotin) LS-C213397

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

COPS8 / COP9 Antibody (aa1-30, FITC) LS-C213399

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

COPS8 / COP9 Antibody (aa1-30, APC) LS-C213396

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

COPS8 / COP9 Antibody (aa1-30, Azide-free, HRP) LS-C213398

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

COPS8 / COP9 Antibody (aa1-30, PE) LS-C213400

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

COPS8 / COP9 Antibody LS-C307816

Antibody:

COPS8 / COP9 Mouse anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

COPS8 / COP9 Antibody LS-C807077

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

COPS8 / COP9 Antibody LS-C765735

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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COPS8 / COP9 Antibody (C-Terminus) LS-C116463

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

COPS8 / COP9 Antibody (C-Terminus, HRP) LS-C455749

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

COPS8 / COP9 Antibody (C-Terminus, Biotin) LS-C455746

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

COPS8 / COP9 Antibody (C-Terminus, FITC) LS-C455747

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

COPS8 / COP9 Antibody LS-C747824

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

COPS8 / COP9 Antibody (aa1-30) LS-C166946

Antibody:

COPS8 / COP9 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Viewing 1-25 of 35 product results

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