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Anti-COPS3 / CSN3 Antibody LS-C155260

Ordering

Wt. Vol. Conc. Price
- 100 µl 0.4 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular COPS3 / CSN3 Antibodies

Anti-COPS3 / CSN3 Antibody (aa374-423) IHC-plus™ LS-B9246
Rabbit Polyclonal (IgG) to Human COPS3 / CSN3
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-COPS3 / CSN3 Antibody (aa324-423, APC) LS-C276536
Mouse Monoclonal (IgG2a) to Human COPS3 / CSN3
Human
ICC, Western blot, ELISA
APC Conjugated
Anti-COPS3 / CSN3 Antibody (aa324-423, FITC) LS-C276539
Mouse Monoclonal (IgG2a) to Human COPS3 / CSN3
Human
ICC, Western blot, ELISA
FITC Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human COPS3 / CSN3
Human, Rat
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated

Details

Human COPS3 / CSN3
Rabbit
Human, Rat (tested or 100% immunogen sequence identity)
Mouse, Bovine, Chicken, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:100 - 1:1000)
  • ICC (1:100 - 1:1000)
  • Immunofluorescence (1:100 - 1:1000)
  • Western blot (1:500 - 1:3000)

Specificity and Use

COPS3 / CSN3 antibody was raised against recombinant fragment corresponding to a region within amino acids 139 and 390 of COPS3 (SwissProt Q9UNS2). Percent identity by BLAST analysis: Human, Rat (100%); Mouse (99%); Chicken (98%); Bovine (97%); Xenopus, Zebrafish (94%).
Human COPS3
Suggested starting dilutions are as follows: Western blot: 1:500-1:3000, IHC-Paraffin: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Packaging

PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal
Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.
For research use only.

About COPS3 / CSN3

Q9UNS2 NM_003653 NP_003644.2

COPS3 Antibody, COP9 complex subunit 3 Antibody, SGN3 Antibody, Signalosome subunit 3 Antibody

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.

Immunohistochemistry

Immunohistochemistry
IHC of paraffin-embedded Colon ca, using COPS3 antibody at 1:250 dilution.

Immunofluorescence

Immunofluorescence
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using COPS3 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.

Western blot

Western blot
Sample (30 ug of whole cell lysate) A: HeLa 10% SDS PAGE COPS3 antibody diluted at 1:3000
 

Requested From: United States
Date Requested: 12/5/2016

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