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COPS3 / CSN3
COP9 signalosome subunit 3
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
| Gene Name: | COP9 signalosome subunit 3 |
| Synonyms: | COPS3, COP9 complex subunit 3, SGN3, Signalosome subunit 3 |
| Target Sequences: | NM_003653 NP_003644.2 Q9UNS2 |
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COPS3 / CSN3
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COPS3 / CSN3 Rabbit anti-Human Polyclonal (aa374-423) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
COPS3 / CSN3 Goat anti-Human Polyclonal (aa301-311) Antibody
Xenopus, Chicken, Zebrafish, Insect, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$450
COPS3 / CSN3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Bovine, Rat, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
COPS3 / CSN3 Rabbit anti-Human Polyclonal (340-420 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$294; 100 µl/$360
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
COPS3 / CSN3 Rabbit anti-Human Polyclonal (Met408) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
COPS3 / CSN3 Mouse anti-Human Monoclonal (aa324-423) Antibody
Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$705
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
COPS3 / CSN3 Rabbit anti-Human Polyclonal (aa325-375) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µl/$295; 100 µl/$514
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$386
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
COPS3 / CSN3 Rabbit anti-Human Polyclonal (aa325-375) Antibody
Human
IHC, IHC-P
Unconjugated
2.5 µg/$295; 100 µl/$532
COPS3 / CSN3 Mouse anti-Human Monoclonal (aa224-423) (OTI3E1) Antibody
Human
WB
Unconjugated
100 µl/$434
COPS3 / CSN3 Mouse anti-Human Monoclonal (aa224-423) (Carrier-free) (OTI3E1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
COPS3 / CSN3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
COPS3 / CSN3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
COPS3 / CSN3 Rabbit anti-Human Polyclonal (aa325-375) Antibody
Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
COPS3 / CSN3 Rabbit anti-Human Polyclonal (aa24-181) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
COPS3 / CSN3 Rabbit anti-Human Polyclonal (aa98-130) Antibody
Human
WB
Unconjugated
400 µl/$393
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of 54
product results
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