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Anti-COMT Antibody (aa143-192) LS-C107721

Catalog Size Price
LS-C107721-50 50 µg Unavailable

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100% Guaranteed
Rabbit Polyclonal (IgG) to Human COMT
Human, Monkey, Bovine, Dog, Horse, Pig, Rabbit
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human COMT
Rabbit
Human, Monkey, Bovine, Dog, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Mouse, Rat, Bat, Guinea pig, Chicken, Xenopus (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

COMT antibody was raised against synthetic peptide located between aa143-192 of human COMT (P21964, NP_000745). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Horse, Pig (100%); Mouse, Rat, Panda, Bat, Guinea pig, Xenopus (92%); Turkey, Chicken (91%); Elephant, Rabbit (85%).
LS-E16284 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C107721. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa143-192
Human COMT
Western Blot: Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:1562500.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
For research use only.

About COMT

P21964 NM_007310 NP_009294.1

COMT Antibody, Catechol O-methyltransferase Antibody, Catechol-O-methyltransferase Antibody

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease.

Western blot

COMT antibody LS-C107721 Western blot of Fetal Stomach lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
COMT antibody LS-C107721 Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 5/20/2018

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