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Anti-Complement C6 Antibody (C-Terminus, clone 056B-214.2.4.2) IHC-plus™ LS-B3294

Note: This antibody replaces LS-C45004

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular Complement C6 Antibodies

Anti-Complement C6 Antibody (C-Terminus, clone 056B-214.2.4.2) IHC-plus™ LS-B3294
Mouse Monoclonal [clone 056B-214.2.4.2] (IgG1) to Human Complement C6
Human
IHC - Paraffin, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image
Anti-Complement C6 Antibody (aa37-66, Biotin) LS-C206469
Rabbit Polyclonal (IgG) to Human Complement C6
Human
IHC, Western blot, Flow Cytometry, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 056B-214.2.4.2] (IgG1) to Human Complement C6
Human
IHC - Paraffin, Flow Cytometry, ELISA
Unconjugated

Details

Human Complement C6
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [056B-214.2.4.2]
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Flow Cytometry
  • ELISA

Specificity and Use

Complement C6 antibody was raised against purified human C6.
C-Terminus
Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.
Immunohistochemistry: LS-B3294 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3294 was determined to be 10 ug/ml. Histology Positive Control Tissue: Kidney from post streptococcal glomerulonephritis patients.

Packaging

Borate buffered saline, 0.09% sodium azide. Sourced in Ascites.
+4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.
For research use only.

About Complement C6

P13671 NM_000065 NP_000056.2

C6 Antibody, Complement component C6 Antibody, Complement C6 Antibody, Complement component 6 Antibody

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.

Immunohistochemistry

Immunohistochemistry
Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Requested From: United States
Date Requested: 12/8/2016

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