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Anti-Complement C5 Antibody (clone 557) LS-C14521

Note: This antibody replaces LS-C79715

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $605
Inquire for larger quantities

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Mouse Monoclonal [clone 557] (IgG2b) to Human Complement C5
Human
Western blot, ELISA
Unconjugated

Details

Human Complement C5
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [557]
Protein G purified

Applications

Western blot, ELISA

Specificity and Use

Complement C5 antibody was raised against human C5.
Recognizes an epitope of human C5 and C5a. Capable in inhibiting the binding of C5a to the C5a receptor through a competitive mechanism. Does not block the cleavage of C5 into C5a and C5b.
ELISA: Used as detection antibody (see J Immunol Methods. 1988 Jul 22;111(2):241-52.). Western Blot: 1:1000. Incubate for 2 hours on nitrocellulose. Optimal dilutions to be determined by the researcher.

Packaging

PBS, 0.1% BSA
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About Complement C5

P01031 NM_001735 NP_001726.2

C5 Antibody, Anaphylatoxin C5a analog Antibody, CPAMD4 Antibody, Complement C5 Antibody, Complement component 5 Antibody

Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process.

Requested From: United States
Date Requested: 9/29/2016

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