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| Catalog Number | Size | Price |
|---|---|---|
| LS-B8738-50 | 50 µg (1 mg/ml) | $505 |
IHC‑plus™ Monoclonal Mouse anti‑Human Complement C4c Antibody (clone 10‑12, IHC, WB) LS‑B8738
IHC‑plus™ Monoclonal Mouse anti‑Human Complement C4c Antibody (clone 10‑12, IHC, WB) LS‑B8738
Note: This antibody replaces LS-C44977
Antibody:
Complement C4c Mouse anti-Human Monoclonal (10-12) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
Complement C4c Mouse anti-Human Monoclonal (10-12) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Complement C4c antibody LS-B8738 is an unconjugated mouse monoclonal antibody to human Complement C4c. Validated for ELISA, Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
10-12
Conjugations
Unconjugated
Purification
Protein A purified from ascites
Modifications
Unmodified
Immunogen
Purified human C4c.
Specificity
Recognizes complement component 4c (C4c). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. iC4b is further degraded into the inactive fragments C4d and C4c. C4c consists of two a-chain fragments, alpha 4 (13 kD) and alpha 3 (25 kD) linked to a beta chain through disulphide bridges and a gamma chain. It is expressed in the blood plasma. Binds both C4c and C4 and so is not suitable for all ELISA applications.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- IHC - Frozen
- Western blot
- Flow Cytometry
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
ELISA: Binds both C4c and C4 and so is not suitable for all ELISA applications.
Presentation
BBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Validation
Anti-Complement C4c antibody IHC staining of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Complement C4c antibody IHC staining of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
IHC-plus™ Complement C4c Antibody (clone 10-12) for IHC, WB/Western, Flow, ELISA LS-B8738 has an LSBio Rating of
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
ICC, Western blot, Immunoprecipitation
Species:
Human
Applications:
ICC, Western blot, Immunoprecipitation
Species:
Human
Applications:
IHC, IHC - Frozen, Western blot, ELISA
Species:
Human
Applications:
IHC, Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Frozen, Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
ICC, Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/17/2024
Date Requested: 4/17/2024
