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Anti-Complement C3c Antibody (HRP) LS-C185002

Catalog Size Price
LS-C185002-1000 1000 µl Unavailable

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100% Guaranteed
Goat Polyclonal (IgG) to Guinea pig Complement C3c
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ELISA, Immunoelectrophoresis
HRP Conjugated

Details

Guinea pig Complement C3c
Goat
Guinea pig (tested or 100% immunogen sequence identity)
IgG Polyclonal
Horseradish Peroxidase
Purified
Unmodified

Applications

  • ELISA
  • Immunoelectrophoresis

Specificity and Use

Complement C3c antibody was raised against c3c isolated and purified from pooled normal guinea pig serum.
Guinea pig serum Complement C3, C3c. Reacts with both native and activated C3. May also react with the fragments C3b, C3bi and C3dg, since they all carry antigenic epitopes of the C3c domain. In immunoelectrophoresis against fresh guinea pig serum, a single precipitin line is obtained in the beta-1 region representing native C3. Against serum containing partly activated C3, a precipitin line is obtained which extends from the beta-1 into the alpha-2 region, demonstrating a gradient. In old serum containing totally activated C3 a single precipitin line in the alpha-2 region is obtained. Also reacts with the fragments C3b, C3bi and smaller fragments, since they all carry antigenic determinants of the C3c domain. Does not react with any other proteins component of guinea pig serum or plasma.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from PBS, pH 7
1,000 µl Sterile distilled water
Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C. Protect from light.
For research use only.

About Complement C3c

C3c is the major fragment resulting from the C3 cleavage by C3 convertase and factor i. It is composed of an intact beta chain bound to two fragments of the alpha chain.

Requested From: 
Date Requested: 5/21/2018

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