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Anti-Complement C3c Antibody (FITC) LS-C187631

Ordering

Wt. Vol. Conc. Price
1000 µg - 1 mg/ml $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular Complement C3c Antibodies

Anti-Complement C3c Antibody (FITC) LS-C42306
Sheep Polyclonal (IgG) to Human Complement C3c
Human
IHC - Paraffin, IHC - Frozen, ELISA
FITC Conjugated
Immunohistochemistry Image
Anti-Complement C3c Antibody IHC-plus™ LS-B7932
Rabbit Polyclonal to Human Complement C3c
Human
IHC - Paraffin, Immunodiffusion
Unconjugated
Immunohistochemistry Image
Anti-Complement C3c Antibody (FITC) LS-C185015
Goat Polyclonal (IgG) to Rabbit Complement C3c
Rabbit
ELISA, Immunoelectrophoresis
FITC Conjugated

100% Guaranteed 100% Guaranteed
Sheep Polyclonal (IgG) to Human Complement C3c
Human
IHC - Paraffin, IHC - Frozen, Immunofluorescence, ELISA (applications tested for the base form of this product only)
FITC Conjugated

Details

Human Complement C3c
Sheep
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Fluorescein. Also available Unconjugated or conjugated with HRP, FITC.
Affinity purified
Unmodified

Applications

  • IHC - Paraffin
  • IHC - Frozen
  • Immunofluorescence (1:10 - 1:50)
  • ELISA (1:500 - 1:50000)
  • (applications tested for the base form of this product only)

Specificity and Use

Complement C3c antibody was raised against native human C3c purified from serum.
Detects human complement 3c, a polypeptide fragment which is present in C3. C3 plays a central role in the activation of the complement system. Processing of C3 by C3 convertase is the central reaction in both classical and alternative complement pathways, resulting in C3a and C3b. C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates, and help to initiate the complement cascade, potentially resulting in cellular apoptosis. C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3b is rapidly split in two positions by factor I and a cofactor to form iC3b (inactivated C3b) and C3f which is released. Then iC3b is slowly cleaved (possibly by factor I) to form C3c and C3dg. Defects in C3 can result in susceptibility to pyogenic infection. Shows minimal reactivity with related serum proteins.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About Complement C3c

C3c is the major fragment resulting from the C3 cleavage by C3 convertase and factor i. It is composed of an intact beta chain bound to two fragments of the alpha chain.

Immunohistochemistry

Immunohistochemistry
Anti-Complement C3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5757 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry
Anti-Complement C3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5757 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Native Human C3c detected using Sheep anti-Human C3c:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/8/2016

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