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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Complement C3 Antibody (clone 11H9) LS‑C22283 Best Seller
Complement C3 antibody LS-C22283 is an unconjugated rat monoclonal antibody to mouse Complement C3. Validated for ELISA, Flow, IHC, IP and WB. Cited in 1 publication.
Antibody
Catalog
Size
Price
LS-C22283-100
100 µg (0.1 mg/ml)
Unavailable

Popular Complement C3 Products

Antibody
Species: Human
Applications: Flow Cytometry, ELISA
Mouse thymocytes incubated with Rabbit Anti-Mouse T cells, then incubated with fresh human serum and stained with LS-C62855. Antibody concentration: 0.5ug/10^6 cells.. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse
Applications: Flow Cytometry, ELISA
Antibody
Species: Human
Applications: Flow Cytometry
Anti-Complement C3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2545 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

Complement C3 antibody LS-C22283 is an unconjugated rat monoclonal antibody to mouse Complement C3. Validated for ELISA, Flow, IHC, IP and WB. Cited in 1 publication.
About Complement C3
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. P01024 NM_000064 NP_000055.2

C3 Antibody, AHUS5 Antibody, ARMD9 Antibody, Complement component C3 Antibody, CPAMD1 Antibody, Complement C3 Antibody, ASP Antibody, Complement component 3 Antibody


Specifications

Target
Mouse Complement C3
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal [11H9]
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot (1:25)
  • Immunoprecipitation
  • Flow Cytometry (1:25)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Complement C3 antibody was raised against mouse Complement C3.
Specificity
Recognizes mouse C3, C3b, iC3b and C3d.
Usage
Suitable for use in ELISA, Western Blot, Immunoprecipitation, Flow Cytometry and Immunohistochemistry. ELISA: Coating antibody. Western Blot: 1:25. Flow Cytometry: 1:25. Immunohistochemistry (Frozen sections): 1:25.
Presentation
PBS, 0.02% sodium azide, 0.1% BSA
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Autoantibody-mediated complement C3a receptor activation contributes to the pathogenesis of preeclampsia. Wang W, Irani RA, Zhang Y, Ramin SM, Blackwell SC, Tao L, Kellems RE, Xia Y. Hypertension. 2012 60:712-21. (IHC; Mouse) [Full Text Article] [PubMed:22868393] [PMC:PMC4131740]

Customer Reviews (0)


Requested From: 
Date Requested: 7/18/2018

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