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Anti-Complement C3 Antibody (aa1580-1592) IHC-plus™ LS-B11161

Note: This antibody replaces LS-C155064
Catalog Size Price
LS-B11161-50 50 µg (0.5 mg/ml) Unavailable

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114 Complement C3 Antibodies

Most Popular Complement C3 Antibodies

Anti-Complement C3 Antibody (clone 11H9) LS-C22283
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Unconjugated
Anti-Complement C3 Antibody (clone 6C9, Biotin) LS-C62849
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Anti-Complement C3 Antibody (clone 6C9, FITC) LS-C62855
Mouse Monoclonal [clone 6C9] (IgG1) to Human Complement C3
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Flow Cytometry Image
Anti-Complement C3 Antibody (clone 10C7, FITC) LS-C62858
Mouse Monoclonal [clone 10C7] (IgG1) to Human Complement C3
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Anti-Complement C3 Antibody (clone 2D8) IHC-plus™ LS-B2545
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Immunohistochemistry Image

100% Guaranteed
Goat Polyclonal to Human Complement C3
Human, Monkey
IHC - Paraffin, ELISA
Unconjugated

Details

Human Complement C3
Goat
Human, Monkey (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ELISA (1:128000)

Specificity and Use

Complement C3 antibody was raised against synthetic peptide QQRTFISPIKCRE from the C-terminus of human Complement C3 (NP_000055.2). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%).
LS-E27967 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B11161. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa1580-1592
Human Complement C3. This antibody is expected to recognize the C3 alpha chain, C3b alpha chain and the C3c alpha chain fragment 2.
Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Preliminary experiments gave an approx 125kD band in Human Liver lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 104kD according to the largest fragment C3 alpha chain (aa672-1663). Although this fragment is glycosylated, we have not yet found support in the literature for the observed size. The 125kD band was successfully blocked by incubation with the immunizing peptide.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About Complement C3

P01024 NM_000064 NP_000055.2

C3 Antibody, AHUS5 Antibody, ARMD9 Antibody, Complement component C3 Antibody, CPAMD1 Antibody, Complement C3 Antibody, ASP Antibody, Complement component 3 Antibody

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process.

Immunohistochemistry

Immunohistochemistry
Anti-Complement C3 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-Complement C3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11161 concentration 5 ug/ml.

Requested From: 
Date Requested: 12/18/2017

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