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Anti-Complement C1q Antibody (clone 3R9/2) LS-C44972

Ordering

Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $465
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Most Popular Complement C1q Antibodies

Anti-Complement C1q Antibody (clone 3R9/2) LS-C44972
Mouse Monoclonal [clone 3R9/2] (IgG1) to Human Complement C1q
Human
IHC - Frozen, Flow Cytometry, ELISA
Unconjugated
Anti-Complement C1q Antibody (clone 242G3) LS-C84856
Mouse Monoclonal [clone 242G3] (IgG1) to Human Complement C1q
Human
Western blot, ELISA, Inhibition
Unconjugated
Anti-Complement C1q Antibody (clone JL-1) LS-C122764
Mouse Monoclonal [clone JL-1] (IgG2b) to Mouse Complement C1q
Mouse, Human, Rat
IHC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 3R9/2] (IgG1) to Human Complement C1q
Human
IHC - Frozen, Flow Cytometry, ELISA
Unconjugated

Details

Human Complement C1q
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [3R9/2]
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Frozen (1:500 - 1:1000)
  • Flow Cytometry
  • ELISA

Specificity and Use

Complement C1q antibody was raised against binds globular head domain of C1q, purified from human plasma.
Recognizes human complement component 1, q subcomponent (C1q), a 156kD secreted protein. C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.
Immunohistology: Strong staining was observed in the glomeruli and in some cases the peritubular capillary (potentially clinically significant).

Packaging

Borate buffered saline, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About Complement C1q

C1q is a 400kDa protein formed from 18 peptide chains in 3 subunits (C1QA, C1QB, and C1QC). Each 6 peptide subunit consists of a Y-shaped pair of triple peptide helices joined at the stem and ending in a globular non-helical head.

Requested From: United States
Date Requested: 12/9/2016

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