COMP / THBS5

cartilage oligomeric matrix protein

May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7.

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Products

Antibodies (91)

ELISA Kits (33)

Proteins (10)

Type

Competitive EIA (1)

Custom (3)

Development Kit (3)

Over-Expression Lysate (2)

Primary (91)

Recombinant (8)

Sandwich (21)

Sandwich CLIA (5)

Target

COMP / THBS5 (134)

Reactivity

Human (58)

Mouse (51)

Rat (49)

Chicken (1)

Dog (3)

Guinea pig (1)

Horse (4)

Monkey (1)

Pig (11)

Porcine (1)

Application

IHC (15)

IHC-Fr (2)

IHC-P (6)

WB (82)

Flo (1)

ELISA (24)

IF (2)

IP (2)

Peptide-ELISA (2)

Host

rabbit (80)

mouse (8)

chicken (2)

rat (1)

Product Group

DevKit DuoPlus (3)

IHCPlus (2)

Isotype

IgG (20)

IgG1 (8)

IgG2a (1)

IgY (2)

Clonality

monoclonal mc (9)

polyclonal pc (82)

Clone

12C4 (1)

4H6G10D2 (1)

MA37C94 (HC484D1) (1)

Format

12 x 8-Well Microstrips (3)

96-Well Microplate (6)

96-Well Strip Plate (21)

Antibody Pair and Standard (3)

APC (6)

APC Conjugated (7)

Azide-free (1)

Biotin Conjugated (9)

Cy3 Conjugated (6)

Cy7 Conjugated (6)

FITC Conjugated (9)

HRP Conjugated (8)

PE Conjugated (7)

Preservative Free (2)

Unconjugated (39)

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Epitope

aa317-455 (10)

aa554-753 (9)

aa123-240 (8)

aa235-423 (8)

aa35-179 (8)

aa40-180 (8)

aa314-343 (7)

N-Terminus (4)

aa20-160 (2)

C-Terminus (1)

Publications

No (133)

Yes (1)

Sample Type

Cell Culture Supernatants (6)

Cell Lysates (5)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (25)

Serum (26)

Tissue Homogenates (9)

Tag

His (6)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Mouse (3)

Rat (2)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (2)

Human Cells (1)

Low Endotoxin Level

Low endotoxin level (1)

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IHC-plus™ COMP / THBS5 Antibody (clone 12C4) LS-B12308

(5.0) Rating

(1) Publication(s)

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal (12C4) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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IHC-plus™ COMP / THBS5 Antibody LS-B13394

(4.0) Rating

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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COMP / THBS5 Antibody (aa314-343) LS-C166937

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa314-343) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

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COMP / THBS5 Antibody LS-C122806

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$657

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COMP / THBS5 Antibody (aa20-160) LS-C375502

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa20-160) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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COMP / THBS5 Antibody (aa20-160) LS-C375498

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa20-160) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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COMP / THBS5 Antibody (N-Terminus) LS-C345420

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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COMP / THBS5 Antibody (N-Terminus, HRP) LS-C442560

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Horse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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COMP / THBS5 Antibody (N-Terminus, Biotin) LS-C442390

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Horse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

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Mouse COMP / THBS5 (Sandwich ELISA) ELISA Kit - LS-F20749

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat COMP / THBS5 (Sandwich ELISA) ELISA Kit - LS-F20777

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human COMP / THBS5 (Sandwich ELISA) ELISA Kit - LS-F2752

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$795

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Mouse COMP / THBS5 (Sandwich ELISA) ELISA Kit - LS-F6076

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$705

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Rat COMP / THBS5 (Sandwich ELISA) ELISA Kit - LS-F11174

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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COMP / THBS5 Antibody (aa314-343, Biotin) LS-C276410

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa314-343) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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COMP / THBS5 Antibody LS-C122808

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

100 µg/$657

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COMP / THBS5 Antibody LS-C401541

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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Human COMP / THBS5 Protein (Recombinant His) (Met1-Ala757) - LS-G97069

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

82.4 kDa

Price:

100 µg/$721

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Mouse COMP / THBS5 (Sandwich ELISA) ELISA Kit - LS-F34517

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human COMP / THBS5 (CLIA) ELISA Kit - LS-F29518

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

COMP / THBS5 Antibody LS-C122807

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$657

Select

COMP / THBS5 Antibody LS-C404832

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

COMP / THBS5 Antibody (aa123-240) LS-C372681

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa123-240) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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COMP / THBS5 Antibody (aa123-240, HRP) LS-C709181

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa123-240) (HRP) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511

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COMP / THBS5 Antibody (aa123-240, Biotin) LS-C685562

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa123-240) (Biotin) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

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