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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Collagen I Antibody LS‑C79493
Collagen I antibody LS-C79493 is an unconjugated goat polyclonal antibody to human Collagen I. Validated for ELISA, ICC and IHC.
Antibody
Catalog
Size
Price
LS-C79493-200
200 µg
Unavailable

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Product Description

Collagen I antibody LS-C79493 is an unconjugated goat polyclonal antibody to human Collagen I. Validated for ELISA, ICC and IHC.
About Collagen I
Type I collagen is the most abundant collagen of the human body which forms large, eosinophilic fibers known as collagen fibers. It is present in scar tissue, the end product when tissue heals by repair, as well as tendons, ligaments, the endomysium of myofibrils, the organic part of bone, the dermis, the dentin and organ capsules. Collagen, type I, alpha 1, also known as alpha-1 type I collagen, is encoded by the COL1A1 gene. Collagen alpha-2(I) chain is encoded by the COL1A2 gene.

Specifications

Target
Human Collagen I
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • ICC (1:10 - 1:20)
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Collagen I antibody was raised against human Type I collagen.
Specificity
Recognizes conformational determinants on human type I collagen as demonstrated by ELISA. Exhibits <10% cross-reactivity with collagen types II, III, IV, V and VI. Has not been tested for cross-reactivity with other extracellular matrix proteins (e. g. laminin, fibronectin). Species cross-reactivity: May cross-react with type I collagen from other species.
Usage
Suitable for use in ELISA, Dot and Slot Blot (non-denaturing), Immunohistochemistry and Immunocytochemistry. Immunocytochemistry: 1:10-1:20. Immunohistochemistry (Frozen): 1:10-1:20.
Presentation
100 mM borate buffered saline, pH 8.0. No preservative added.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/19/2018

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