Human COL4A1 / Collagen IV Alpha1

Rabbit

Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Sheep (tested or 100% immunogen sequence identity)

Rabbit (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide from the C-Terminus of human Collagen IV COL4A1 (ELRTHVSRCQVCMRRT, aa1654-1669 of UniProt P02462). Percent identity by BLAST analysis: Human, Mouse, Rat, Ferret, Sheep, Cat, Bovine, Bat, Hamster, Elephant, Horse, Pig, Opossum, Guinea pig, Dog (100%); Rabbit (94%); Platypus (88%); Xenopus, Trout, Medaka, Catfish, Pufferfish (81%).

aa1654-1669

Human COL4A1 / Collagen IV Alpha1

• Western blot (0.5 - 1 µg/ml)

Collagen alpha-1 (IV) chain is a protein that in humans is encoded by the COL4A1 gene. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in COL4A1 exons 24 and 25 are associated with HANAC (autosomal dominant hereditary angiopathy with nephropathy,aneurysms, and muscle cramps).

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P02462 NCBI: NM_001845 NP_001836.3