Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse, Human, Rat, Dog, Horse
(tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
A synthetic peptide (GYPSPHYRWKQ) as part of mouse contactin-6 conjugated to KLH. Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Mouse, Rat, Panda, Dog, Horse (100%); Gorilla, Marmoset (91%); Elephant, Bovine, Opossum, Turkey, Chicken (82%).
Stains the NB3 in DRG, where it nicely stains a subpopulation of neurons and in the trigeminal nerve root, where staining is restricted to the oligodendrocytes. Species cross-reactivity: Confirmed to react with rat Contactin-6 and expected to recognize human and mouse Contactin-6 as well.
Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.