Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CNOT8

CCR4-NOT transcription complex, subunit 8

Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

Gene Name: CCR4-NOT transcription complex, subunit 8
Synonyms: CNOT8, CAF1-like protein, CALIFp, CCR4-associated factor 8, CAF2, HCAF1, POP2, CAF1, CALIF
Target Sequences: NM_004779 NP_004770.4 Q9UFF9

Publications (1)

1
PABP Cooperates with the CCR4-NOT Complex to Promote mRNA Deadenylation and Block Precocious Decay. Hyerim Yi, Joha Park, Minju Ha, Jaechul Lim, Hyeshik Chang, V Narry Kim. Molecular cell. 2018 Jun;70:1081-1088e5. [Full Text Article] [PubMed:29932901] Related Antibodies: LS-C99242.

☰ Filters
Antibodies (35)
Proteins (6)
Over-Expression Lysate (2)
Primary (35)
Recombinant (4)
CNOT8 (41)
Human (33)
Mouse (12)
Rat (10)
Bat (6)
Bovine (6)
Chicken (3)
Chimpanzee (6)
Dog (6)
Gibbon (3)
Guinea pig (6)
Horse (6)
Monkey (7)
Orangutan (3)
Pig (6)
Rabbit (6)
IHC (6)
IHC-P (4)
WB (34)
Flo (1)
ELISA (20)
IF (1)
Peptide-ELISA (1)
rabbit (29)
mouse (6)
Product Group
IHCPlus (1)
IgG (18)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (29)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (14)
aa227-255 (7)
aa33-60 (7)
C-Terminus (4)
N-Terminus (4)
aa1-292 (1)
aa201-292 (1)
No (40)
Yes (1)
GST (1)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (3)
CNOT8 Antibody - Formalin-fixed and paraffin-embedded human colon carcinoma with CNOT8 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
CNOT8 Rabbit anti-Human Polyclonal (aa227-255) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
CNOT8 Mouse anti-Human Monoclonal (aa201-292) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
CNOT8 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
CNOT8 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
CNOT8 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
CNOT8 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
CNOT8 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
CNOT8 Antibody - HCAF1 / CNOT8 antibody Western Blot of Mouse Testis.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CNOT8 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$424
CNOT8 Antibody - HCAF1 / CNOT8 antibody Western Blot of Mouse Testis.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CNOT8 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$424
CNOT8 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CNOT8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
CNOT8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
CNOT8 Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer using antibody at 1:100 dilution.
Select
CNOT8 Rabbit anti-Human Polyclonal (aa1-292) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CNOT8 Antibody
Select
CNOT8 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
CNOT8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
CNOT8 Rabbit anti-Human Polyclonal (aa227-255) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CNOT8 Rabbit anti-Human Polyclonal (aa227-255) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
CNOT8 Rabbit anti-Human Polyclonal (aa227-255) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
CNOT8 Rabbit anti-Human Polyclonal (aa227-255) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
CNOT8 Rabbit anti-Human Polyclonal (aa227-255) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
CNOT8 Rabbit anti-Human Polyclonal (aa33-60) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CNOT8 Rabbit anti-Human Polyclonal (aa33-60) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
CNOT8 Rabbit anti-Human Polyclonal (aa33-60) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
CNOT8 Rabbit anti-Human Polyclonal (aa33-60) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
CNOT8 Rabbit anti-Human Polyclonal (aa33-60) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
CNOT8 Antibody - Western blot analysis of extracts of Jurkat cells using CNOT8 antibody. The lane on the left was treated with blocking peptide.
Select
CNOT8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 41 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).