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CNNM2 is a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: | cyclin M2 |
Synonyms: | CNNM2, ACDP2, Cyclin M2, Cyclin-M2, Metal transporter CNNM2 |
Target Sequences: | NM_017649 NP_060119.3 Q9H8M5 |
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