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CNGA3

cyclic nucleotide gated channel alpha 3

Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

Gene Name: cyclic nucleotide gated channel alpha 3
Family/Subfamily: Ion Channel , Cyclic nucleotide gated channel
Synonyms: CNGA3, CCNCa, CCNCalpha, CCNC1, CNG channel alpha-3, CNG3, ACHM2, Achromatopsia 2, MCNG3, CNCG3, CNG-3
Target Sequences: NM_001298 NP_001289.1 Q16281

Publications (1)

1
Morphological and physiological species-dependent characteristics of the rodent Grueneberg ganglion. Brechbühl J, Klaey M, Moine F, Bovay E, Hurni N, Nenniger-Tosato M, Broillet MC. Frontiers in neuroanatomy. 2014 8:87. (WB; Rat) [Full Text Article] [PubMed:25221478] [PMC:PMC4145810]

☰ Filters
Antibodies (11)
Proteins (5)
ELISA Kits (1)
Over-Expression Lysate (4)
Primary (11)
Recombinant (1)
Sandwich (1)
CNGA3 (17)
Human (9)
Mouse (4)
Rat (4)
Chicken (1)
IHC (2)
IHC-P (2)
WB (10)
ELISA (8)
Peptide-ELISA (1)
rabbit (11)
Product Group
IHCPlus (1)
IgG (9)
polyclonal pc (11)
96-Well Strip Plate (1)
Unconjugated (11)
C-Terminus (1)
N-Terminus (1)
aa1-165 (1)
aa398-417 (1)
No (17)
Cell Lysates (1)
Tissue Homogenates (1)
GST (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
CNGA3 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CNGA3 Rabbit anti-Human Polyclonal (aa1-165) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CNGA3 Antibody - Western blot analysis of Mouse kidney and brain tissue, using CNGA3 Polyclonal Antibody at dilution of 1:500.
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CNGA3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CNGA3 Antibody - Western blot analysis of Mouse kidney and brain tissue, using CNGA3 Polyclonal Antibody at dilution of 1:500.
Select
CNGA3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CNGA3 Antibody - Immunohistochemistry of paraffin-embedded Human rectal tissue at dilution 1:100
Select
CNGA3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
CNGA3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Select
CNGA3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
CNGA3 Rabbit anti-Chicken Polyclonal (aa398-417) Antibody
Chicken
ELISA, WB
Unconjugated
0.1 mg/$379
CNGA3 Antibody - Western blot analysis of CNGA3 using COLO205 whole cells lysates
Select
CNGA3 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
CNGA3 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
ELISA, WB
Unconjugated
100 µg/$832
Select
CNGA3 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat
ELISA, WB
Unconjugated
100 µg/$832
Select
CNGA3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CNGA3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
CNGA3 Protein - 12.5% SDS-PAGE of human CNGA3 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
103.3 kDa
10 µg/$479; 25 µg/$670
CNGA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
76.7 kDa
20 µg/$215
CNGA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
78.7 kDa
20 µg/$215
CNGA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
76.7 kDa
100 µg/$710
CNGA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
78.7 kDa
100 µg/$710
Viewing 1-17 of 17 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).