Bacteria Clostridium difficile A Toxin

Rabbit

Bacteria (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Protein G purified

Unmodified

Synthetic peptide corresponding to the aa 2123-2132 of the native molecule conjugated to Keyhole limpet Hemocyanin. Peptide sequence: CTIDGKKYYFN. Percent identity by BLAST analysis: Slime mold, Clostridium, Sablefish (80%).

aa2123-2132

Clostridium difficile Toxin A, a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.

• ELISA

PBS, 0.09% Sodium Azide

Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.