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CLEC7A / Dectin 1
C-type lectin domain family 7, member A
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.
| Gene Name: | C-type lectin domain family 7, member A |
| Synonyms: | CLEC7A, BGR, CANDF4, CLECSF12, Dectin-1, DC-associated C-type lectin 1, DECTIN1, HDectin-1, Beta-glucan receptor, Lectin-like receptor 1, CD369 |
| Target Sequences: | NM_022570 NP_072092.2 Q9BXN2 |
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CLEC7A / Dectin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
CLEC7A / Dectin 1 Rat anti-Mouse Monoclonal Antibody
Mouse
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$634; 250 µg/$878
CLEC7A / Dectin 1 Rat anti-Mouse Monoclonal (Biotin) Antibody
Mouse
Flo, IHC, IP
Biotin Conjugated
100 µl/$907
CLEC7A / Dectin 1 Rat anti-Mouse Monoclonal (FITC) Antibody
Mouse
Flo, IHC, IP
FITC Conjugated
100 µl/$907
CLEC7A / Dectin 1 Rat anti-Mouse Monoclonal (PE) Antibody
Mouse
Flo, IHC, IP
PE Conjugated
100 µl/$907
CLEC7A / Dectin 1 Rabbit anti-Human Polyclonal Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
100 µl/$575
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$923
CLEC7A / Dectin 1 Rabbit anti-Human Polyclonal (aa70-98) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CLEC7A / Dectin 1 Mouse anti-Human Monoclonal (4G2G6) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$459
CLEC7A / Dectin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CLEC7A / Dectin 1 Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µg/$562; 200 µg/$755
CLEC7A / Dectin 1 Rat anti-Mouse Monoclonal (APC) Antibody
Mouse
Flo
APC Conjugated
100 Tests/$846
HEK 293 Cells
Human IgG1 Fc
Less than 0.01 EU/µg protein (determined by LAL method).
~56kDa (SDS-PAGE)
50 µg/$414
CLEC7A / Dectin 1 Rat anti-Mouse Monoclonal (2A11) Antibody
Mouse
Flo, IHC-Fr, IP
Unconjugated
25 µg/$301; 0.1 mg/$435; 0.25 mg/$545
CLEC7A / Dectin 1 Rat anti-Mouse Monoclonal (Biotin) (2A11) Antibody
Mouse
Flo
Biotin Conjugated
0.1 mg/$495
CLEC7A / Dectin 1 Mouse anti-Human Monoclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$884
CLEC7A / Dectin 1 Rat anti-Mouse Monoclonal Antibody
Mouse
Flo, Func, IHC, IHC-Fr, IP
Unconjugated
500 µg/$1,201
CLEC7A / Dectin 1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
Flo, ICC, IF
Unconjugated
100 µl/$412
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
293T Cells
Myc-DDK (Flag)
27.4 kDa
20 µg/$150
Wheat Germ Extract
GST
34.21 kDa
10 µg/$479; 25 µg/$670
CLEC7A / Dectin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
CLEC7A / Dectin 1 Rabbit anti-Human Polyclonal (aa70-98) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
CLEC7A / Dectin 1 Rabbit anti-Human Polyclonal (aa70-98) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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