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Anti-CLEC6A / Dectin 2 Antibody (Extracellular Domain, FITC) LS-C44830

Note: This antibody replaces LS-C57944

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $285
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CLEC6A / Dectin 2 Antibodies

Anti-CLEC6A / Dectin 2 Antibody (Extracellular Domain) LS-C123384
Rat Monoclonal (IgG2a) to Mouse CLEC6A / Dectin 2
Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-CLEC6A / Dectin 2 Antibody (aa46-209) LS-C125446
Mouse Monoclonal (IgG1) to Human CLEC6A / Dectin 2
Human
Flow Cytometry, ELISA
Unconjugated
Anti-CLEC6A / Dectin 2 Antibody (aa75-125, clone IMG3D1) LS-C148786
Mouse Monoclonal [clone IMG3D1] (IgG3,k) to Human CLEC6A / Dectin 2
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2a) to Mouse CLEC6A / Dectin 2
Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated

Details

Mouse CLEC6A / Dectin 2
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Fluorescein. Also available Unconjugated or conjugated with RPE.
Protein G purified
Unmodified

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:10)
  • (applications tested for the base form of this product only)

Specificity and Use

CLEC6A / Dectin 2 antibody was raised against dectin-2 (extracellular domain) Fc Fusion protein.
Extracellular Domain
Recognizes mouse DC-associated C-type lectin-2 (Dectin-2), a type II transmembrane protein that is a member of the C-type lectin superfamily. In mouse, dectin-2 is predominantly expressed on tissue macrophages and some dendritic cells. Clone D2.11E4 does not stain brain microglia or meningeal macrophages. Significant expression of Dectin-2 has been reported on macrophages in the red pulp and marginal zones of the spleen, Kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin-2 but transient up-regulation of expression has been demonstrated on monocytes at sites of inflammation. The function of dectin-2 has not been fully determined but studies suggest a possible role in immune-surveillance.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.

Packaging

PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
Short term 4 C, Long term -20 C, Product is photosensitive and should be protected from light. Avoid freeze-thaw cycles.
For research use only.

About CLEC6A / Dectin 2

Q6EIG7 Q6EIG7

CLEC6A Antibody, CLEC4N Antibody, CLECSF10 Antibody, Dectin-2 Antibody, Dectin 2 Antibody, DC-associated C-type lectin 2 Antibody, DECTIN2 Antibody

Binds high-mannose carbohydrates in a Ca2+-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses.

Requested From: United States
Date Requested: 12/3/2016

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