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CLDN5 / Claudin 5

claudin 5

CLDN5 / Claudin 5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: claudin 5
Family/Subfamily: Claudin , not assigned-Claudin
Synonyms: CLDN5, BEC1, AWAL, Claudin-5, CPETRL1, TMDVCF, TMVCF, Claudin 5
Target Sequences: NM_003277 NP_003268.2 O00501

Publications (3)

1
One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood-brain barrier permeability in fed or overnight fasted rats. Rijnsburger M, Unmehopa UA, Eggels L, , Serlie MJ, la Fleur SE,. Nutritional neuroscience. 2017 29:1-10. (WB; Human) [Full Text Article] [PubMed:29284375] Related Antibodies: LS-B5971.
2
Simulating vasogenic brain edema using chronic VEGF infusion. Martin Piazza, Jeeva Munasinghe, Roger Murayi, Nancy Edwards, Blake Montgomery, Stuart Walbridge, Marsha Merrill, Prashant Chittiboina. Journal of neurosurgery. 2017 October;127:905-916. [Full Text Article] [PubMed:28059647] [PMC:PMC5542877] Related Antibodies: LS-B11331.
3
Altered DNA methylation profile in idiopathic pulmonary fibrosis. Sanders YY, Ambalavanan N, Halloran B, Zhang X, Liu H, Crossman DK, Bray M, Zhang K, Thannickal VJ, Hagood JS. American journal of respiratory and critical care medicine. 2012 Sep;186:525-35. [Full Text Article] [PubMed:22700861] [PMC:PMC3480526] Related Antibodies: LS-B5971.

☰ Filters
Antibodies (44)
ELISA Kits (10)
Proteins (5)
Cell-Based (1)
Over-Expression Lysate (3)
Primary (44)
Recombinant (2)
Sandwich (9)
CLDN5 / Claudin 5 (59)
Human (40)
Mouse (35)
Rat (29)
Bovine (2)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Monkey (4)
Orangutan (1)
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IHC (21)
IHC-P (8)
WB (30)
Flo (2)
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ICC (2)
IF (10)
IP (1)
Peptide-ELISA (4)
rabbit (34)
mouse (10)
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monoclonal mc (10)
polyclonal pc (34)
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Unconjugated (27)
C-Terminus (7)
150-230 aa (2)
aa169-218 (2)
pTyr217 (2)
140-220 aa, C-terminal (1)
aa171-220 (1)
aa181-218 (1)
aa191-218 (1)
No (57)
Yes (2)
Adherent Cell Cultures (1)
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Cell Lysates (4)
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GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
CLDN5 / Claudin 5 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal (aa169-218) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
CLDN5 / Claudin 5 Antibody - Anti-CLDN5 / Claudin 5 antibody IHC of rat lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CLDN5 / Claudin 5 Mouse anti-Mouse Monoclonal Antibody
Mouse, Rat
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
CLDN5 / Claudin 5 Antibody - Anti-CLDN5 / Claudin 5 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal (aa171-220) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CLDN5 / Claudin 5 Antibody - Immunohistochemical analysis of Claudin 5 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
CLDN5 / Claudin 5 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
CLDN5 / Claudin 5 Protein - 12.5% SDS-PAGE of human CLDN5 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.5 kDa
2 µg/$439
CLDN5 / Claudin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
CLDN5 / Claudin 5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$893
CLDN5 / Claudin 5 Antibody - IF using Claudin-5 Antibody, Alexa Fluor® 488, Alexa Fluor® 488 conjugate (4C3C2)
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CLDN5 / Claudin 5 Mouse anti-Mouse Monoclonal (AF488) (4C3C2) Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IP, WB
AF488 Conjugated
100 µg/$541
CLDN5 / Claudin 5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
CLDN5 / Claudin 5 Antibody - Anti-CLDN5 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLDN5.
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CLDN5 / Claudin 5 Mouse anti-Human Monoclonal (OTI1G4) Antibody
Flo, IF
Unconjugated
100 µl/$434
CLDN5 / Claudin 5 Antibody - Anti-CLDN5 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLDN5.
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CLDN5 / Claudin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI1G4) Antibody
Human
Flo, IF
Unconjugated, Carrier-free
100 µg/$511
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal (aa169-218) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
CLDN5 / Claudin 5 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
CLDN5 / Claudin 5 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC-P, WB
Unconjugated
250 µl/$485
CLDN5 / Claudin 5 Antibody - Western blot of Claudin-5 antibody
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal (140-220 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CLDN5 / Claudin 5 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
60 µl/$307; 120 µl/$367; 200 µl/$457
CLDN5 / Claudin 5 Antibody - Immunofluorescence analysis of NIH/3T3 cells using CLDN5 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CLDN5 / Claudin 5 Antibody - Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Dog, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
CLDN5 / Claudin 5 Antibody - Immunohistochemistry image of paraffin-embedded human lung cancer at a dilution of 1:100
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal (aa181-218) Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
CLDN5 / Claudin 5 Antibody - Staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CLDN5 / Claudin 5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
23 kDa
20 µg/$150
CLDN5 / Claudin 5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CLDN5 / Claudin 5 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
CLDN5 / Claudin 5 Antibody - Western blot of Claudin 5 expression in A549 cell
Select
CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Bovine, Rat, Pig, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
CLDN5 / Claudin 5 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using Claudin 5 antibody.
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CLDN5 / Claudin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 59 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).