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Anti-CLDN1 / Claudin 1 Antibody (C-Terminus, clone 2H10D10) LS-C6141

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $560
Inquire for larger quantities

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Mouse Monoclonal [clone 2H10D10] (IgG1,k) to Human CLDN1 / Claudin 1
Human, Mouse, Rat, Dog
IHC - Frozen, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human CLDN1 / Claudin 1
Mouse
Human, Mouse, Rat, Dog (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [2H10D10]
Protein A purified

Applications

IHC - Frozen, Immunofluorescence (1 - 5 µg/ml), Western blot (1 - 3 µg/ml), Immunoprecipitation, ELISA (0.1 - 1 µg/ml)

Specificity and Use

CLDN1 / Claudin 1 antibody was raised against synthetic peptide derived from the C-terminal region of the human and mouse claudin-1 proteins.
C-Terminus
Specific for the C-terminal region of the human claudin-1 protein. On Western Blots, it identifies the target band at ~22kD. Reactivity has been confirmed with human Caco-2 and canine MDCK cell lysates, mouse kidney and intestinal lysates, frozen mouse intestine (jejunum) tissue, and rat kidney homogenates.
Suitable for use in ELISA, Western Blot, Immunofluorescence, Immunoprecipitation and Immunohistochemistry. ELISA: 0.1-1 ug/ml. Western Blot: 1-3 ug/ml. Immunofluorescence: 1-5 ug/ml. Immunoprecipitation: 10 ug/test. Immunohistochemistry (Frozen): 5-10 ug/ml.

Packaging

PBS, pH 7.4, 0.1% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CLDN1 / Claudin 1

O95832 NM_021101 NP_066924.1

CLDN1 Antibody, Claudin-1 Antibody, Claudin 1 Antibody, ILVASC Antibody, SEMP1 Antibody, CLD1 Antibody

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability.

Requested From: United States
Date Requested: 10/1/2016

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