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CLC-7 / CLCN7

chloride channel, voltage-sensitive 7

CLC-7 / CLCN7 belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Gene Name: chloride channel, voltage-sensitive 7
Family/Subfamily: Ion Channel , Chloride channel - CLC
Synonyms: CLCN7, Chloride channel 7, CLC7, OPTA2, Chloride channel protein 7, CLC-7, OPTB4, PPP1R63
Target Sequences: NM_001287 NP_001278.1 P51798

☰ Filters
Antibodies (24)
Proteins (3)
Over-Expression Lysate (2)
Primary (24)
Recombinant (1)
CLC-7 / CLCN7 (27)
Human (21)
Mouse (11)
Rat (11)
IHC (13)
IHC-P (4)
WB (20)
ELISA (14)
ICC (7)
IF (11)
IP (2)
Peptide-ELISA (3)
rabbit (24)
Product Group
IHCPlus (2)
IgG (21)
polyclonal pc (24)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (19)
aa692-720 (7)
N-Terminus (3)
C-Terminus (2)
10-90 aa, N-terminal (1)
aa10-59 (1)
aa23-72 (1)
aa33-78 (1)
aa50-100 (1)
No (27)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
CLC-7 / CLCN7 Antibody - Immunofluorescent analysis of CLCN7 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
CLC-7 / CLCN7 Antibody - CLCN7 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa692-720) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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CLC-7 / CLCN7 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µl/$801
CLC-7 / CLCN7 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa23-72) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
CLC-7 / CLCN7 Antibody - Western blot of CLC-7 antibody
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CLC-7 / CLCN7 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa10-59) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$832
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa692-720) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa692-720) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa692-720) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa692-720) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa692-720) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa692-720) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
CLC-7 / CLCN7 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CLC-7 / CLCN7 Antibody - Staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CLC-7 / CLCN7 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer tissue  using CLCN7 Polyclonal Antibody at dilution of 1:105(×200)
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa33-78) Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
100 µl/$391
CLC-7 / CLCN7 Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue.
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
CLC-7 / CLCN7 Antibody - Western blot analysis of extracts from A549 cells and LOVO cells, using CLCN7 antibody.
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CLC-7 / CLCN7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
CLC-7 / CLCN7 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µg/$832
Select
CLC-7 / CLCN7 Rabbit Polyclonal Antibody
IP, WB
Unconjugated
10 µl/$295
Select
CLC-7 / CLCN7 Rabbit anti-Human Polyclonal (aa50-100) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
CLC-7 / CLCN7 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-25 of 27 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).