ClC-3 / CLCN3

chloride channel, voltage-sensitive 3

ClC-3 / CLCN3 is a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

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Products

Antibodies (27)

Proteins (1)

Type

Primary (27)

Recombinant (1)

Target

ClC-3 / CLCN3 (28)

Reactivity

Human (27)

Mouse (19)

Rat (19)

Bat (3)

Bovine (3)

Chicken (3)

Chimpanzee (3)

Dog (3)

Frog (2)

Gibbon (3)

Guinea pig (4)

Hamster (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (3)

Rabbit (5)

Xenopus (3)

Zebrafish (3)

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Application

IHC (18)

IHC-P (4)

WB (27)

ELISA (8)

ICC (11)

Peptide-ELISA (1)

Host

rabbit (14)

mouse (12)

rabbit-new zealand white (1)

Isotype

IgG (11)

IgG1 (12)

Clonality

monoclonal mc (12)

polyclonal pc (15)

Clone

S258-5 (12)

Format

AP Conjugated (1)

APC Conjugated (2)

Atto 390 Conjugated (1)

Atto 488 Conjugated (1)

Atto 594 Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (2)

PE Conjugated (1)

PerCP Conjugated (1)

RPE Conjugated (1)

Unconjugated (10)

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Epitope

aa98-115 (10)

aa285-313 (7)

aa620-670 (4)

C-Terminus (2)

Publications

No (28)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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ClC-3 / CLCN3 Antibody (clone S258-5) LS-C150481

Antibody:

ClC-3 / CLCN3 Mouse anti-Human Monoclonal (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

Unconjugated

Price:

100 µg/$442

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ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, Biotin) LS-C228697

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (Biotin) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

Biotin Conjugated

Price:

100 µg/$475

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ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, FITC) LS-C228698

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (FITC) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

FITC Conjugated

Price:

100 µg/$472

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ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, APC) LS-C228695

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (APC) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

APC Conjugated

Price:

100 µg/$478

Select

ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, AP) LS-C228696

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (AP) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

AP Conjugated

Price:

100 µg/$474

Select

ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, RPE) LS-C228701

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (RPE) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

RPE Conjugated

Price:

100 µg/$477

Select

ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, PerCP) LS-C228703

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (PerCP) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

PerCP Conjugated

Price:

100 µg/$478

Select

ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, Atto 390) LS-C229992

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (Atto 390) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

Atto 390 Conjugated

Price:

100 µg/$479

Select

ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, Atto 488) LS-C229993

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (Atto 488) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

Atto 488 Conjugated

Price:

100 µg/$479

Select

ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5, Atto 594) LS-C229995

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (Atto 594) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

Atto 594 Conjugated

Price:

100 µg/$479

• Unconjugated
• Biotin
• FITC
• APC
• AP
• RPE
• PerCP
• More...
  • Atto 390
  • Atto 488
  • Atto 594

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • AP
  • RPE
  • PerCP
  • Atto 390
  • Atto 488
  • Atto 594

Select

ClC-3 / CLCN3 Antibody LS-C806748

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ClC-3 / CLCN3 Antibody (aa98-115, clone S258-5) LS-C309111

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (aa98-115) (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

Unconjugated

Price:

100 µg/$665

Select

ClC-3 / CLCN3 Antibody (aa620-670) LS-C31442

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa620-670) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

Select

ClC-3 / CLCN3 Antibody (aa620-670, HRP) LS-C432784

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa620-670) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

ClC-3 / CLCN3 Antibody (aa620-670, Biotin) LS-C432785

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa620-670) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

ClC-3 / CLCN3 Antibody (aa620-670, FITC) LS-C432783

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa620-670) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ClC-3 / CLCN3 Antibody LS-C829279

Antibody:

ClC-3 / CLCN3 Rabbit-New Zealand White anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

Select

ClC-3 / CLCN3 Antibody (aa285-313) LS-C320418

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa285-313) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

ClC-3 / CLCN3 Antibody (aa285-313, Biotin) LS-C254929

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa285-313) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

ClC-3 / CLCN3 Antibody (aa285-313, FITC) LS-C254930

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa285-313) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

ClC-3 / CLCN3 Antibody (aa285-313, APC) LS-C254928

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa285-313) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

ClC-3 / CLCN3 Antibody (aa285-313, Azide-free, HRP) LS-C254931

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa285-313) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

ClC-3 / CLCN3 Antibody (aa285-313, PE) LS-C254933

Antibody:

ClC-3 / CLCN3 Rabbit anti-Human Polyclonal (aa285-313) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

ClC-3 / CLCN3 Antibody (clone S258-5) LS-C759866

Antibody:

ClC-3 / CLCN3 Mouse anti-Rat Monoclonal (S258-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µg/$537

Select

ClC-3 / CLCN3 Antibody (C-Terminus) LS-C6124

Antibody:

ClC-3 / CLCN3 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody

Reactivity:

Frog, Rat, Rabbit, Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$801

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