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Anti-Chymotrypsin Antibody (clone 4E1) IHC-plus™ LS-B4770

Note: This antibody replaces LS-C27152
Catalog Size Price
LS-B4770-50 50 µg (1 mg/ml) Unavailable

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100% Guaranteed
Mouse Monoclonal [clone 4E1] (IgG3) to Human Chymotrypsin
Human, Mouse, Rat
IHC - Paraffin, IHC - Frozen, Western blot, ELISA


Human Chymotrypsin
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG3 Monoclonal [4E1]
Protein A purified


  • IHC - Paraffin (5 - 10 µg/ml)
  • IHC - Frozen
  • Western blot

Specificity and Use

Chymotrypsin antibody was raised against purified human pancreatic chymotrypsin.
Human chymotrypsin-C, also known as chymotrypsin or caldecrin. Chymotrypsin is a 239 amino acid ~30 kD protease with an additional 13 amino acid propeptide region and a 16 amino acid signal peptide. Variations in the CTRC gene has been associated with susceptibility to hereditary, pancreatitis, a disease characterized by pancreatic inflammation and destruction of the parenchyma.


PBS, pH 7.2, 0.09% sodium azide. Sourced in Ascites.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About Chymotrypsin

Chymotrypsin is a digestive enzyme component of pancreatic juice acting in the duodenum where it performs proteolysis, the breakdown of proteins and polypeptides. Chymotrypsin preferentially cleaves peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a large hydrophobic amino acid (tyrosine, tryptophan, and phenylalanine). These amino acids contain an aromatic ring in their sidechain that fits into a 'hydrophobic pocket' (the S1 position) of the enzyme.


Anti-Chymotrypsin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4770 concentration 5 ug/ml.

Requested From: 
Date Requested: 3/18/2018

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