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CHRNA4 / NACHR

cholinergic receptor, nicotinic, alpha 4 (neuronal)

CHRNA4 / NACHR is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Gene Name: cholinergic receptor, nicotinic, alpha 4 (neuronal)
Family/Subfamily: Ion Channel , Nicotinic acetylcholine receptor
Synonyms: CHRNA4, BFNC, AChR-alpha4, Acra-4, EBN, EBN1, NACHR, NAChR alpha 4, NACRA4, NACHRA4, ENFL1
Target Sequences: NM_000744 NP_000735.1 P43681

☰ Filters
Antibodies (50)
ELISA Kits (5)
Proteins (4)
Custom (4)
Primary (50)
Recombinant (4)
Sandwich CLIA (1)
CHRNA4 / NACHR (59)
Human (41)
Mouse (22)
Rat (13)
Bovine (6)
Chicken (8)
Chimpanzee (6)
Guinea pig (6)
Hamster (3)
Monkey (7)
Rabbit (3)
IHC (1)
WB (48)
ELISA (4)
Peptide-ELISA (5)
rabbit (45)
mouse (3)
goat (2)
IgG (20)
IgG1 (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (48)
4E3 (1)
7B4H1 (1)
96-Well Strip Plate (5)
APC (2)
APC Conjugated (4)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (20)
aa32-249 (8)
aa49-242 (8)
N-Terminus (4)
aa36-85 (4)
C-Terminus (1)
Extracellular Domain (1)
aa1-451 (1)
aa176-208 (1)
aa25-37 (1)
aa29-43 (1)
aa472-503 (1)
No (59)
Plasma (1)
Serum (1)
GST, N-terminus (1)
His-T7 (2)
Myc-DDK (Flag), C-terminus (1)
Human (3)
Mouse (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
CHRNA4 / NACHR Protein - Recombinant Cholinergic Receptor, Nicotinic, Alpha 4 By SDS-PAGE
Select
E. coli
His-T7
29.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CHRNA4 / NACHR Antibody - CHRNA4 antibody (0.3 ug/ml) staining of Rat Brain lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
CHRNA4 / NACHR Goat anti-Human Polyclonal (aa29-43) Antibody
Chicken, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
CHRNA4 / NACHR Protein - Recombinant Cholinergic Receptor, Nicotinic, Alpha 4 By SDS-PAGE
Select
E. coli
His-T7
26.5 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
CHRNA4 / NACHR Antibody - Western blot analysis using CHRNA4 mAb against HEK293 (1) and CHRNA4 (AA: 29-242)-hIgGFc transfected HEK293 (2) cell lysate.
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CHRNA4 / NACHR Mouse anti-Human Monoclonal (7B4H1) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
CHRNA4 / NACHR Antibody - Immunohistochemistry of paraffin-embedded Human brain using CHRNA4 Polyclonal Antibody at dilution of 1:40.
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CHRNA4 / NACHR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
CHRNA4 / NACHR Mouse anti-Human Monoclonal (4E3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CHRNA4 / NACHR Antibody - All lanes: Anti-CHRNA4 Antibody (C-Term) at 1:2000 dilution. Lane 1: A-673 whole cell lysate. Lane 2: HeLa whole cell lysate. Lane 3: HepG2 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 70 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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CHRNA4 / NACHR Rabbit anti-Human Polyclonal (aa472-503) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
CHRNA4 / NACHR Antibody - All lanes: Anti-CHRNA4 Antibody (N-Term) at 1:2000 dilution. Lane 1: HepG2 whole cell lysate. Lane 2: MOLT-4 whole cell lysate. Lane 3: SH-SY5Y whole cell lysate. Lane 4: A-673 whole cell lysate. Lane 5: NCI-H1299 whole cell lysate. Lane 6: Neuro-2a whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 70 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal (aa176-208) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
CHRNA4 / NACHR Antibody - Western blot analysis of CHRNA4 using HuvEc whole cells lysates
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CHRNA4 / NACHR Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
CHRNA4 / NACHR Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CHRNA4 / NACHR Antibody - Western blot of CHRNA4 / NACHR antibody.
Select
CHRNA4 / NACHR Rabbit anti-Mouse Polyclonal (aa32-249) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
CHRNA4 / NACHR Antibody - Western blot of CHRNA4 / NACHR antibody.
Select
CHRNA4 / NACHR Rabbit anti-Mouse Polyclonal (aa32-249) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557
CHRNA4 / NACHR Antibody - Western blot of CHRNA4 / NACHR antibody.
Select
CHRNA4 / NACHR Rabbit anti-Mouse Polyclonal (aa32-249) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
CHRNA4 / NACHR Antibody - Western blot of CHRNA4 / NACHR antibody.
Select
CHRNA4 / NACHR Rabbit anti-Mouse Polyclonal (aa32-249) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
CHRNA4 / NACHR Antibody - Western blot of CHRNA4 / NACHR antibody.
Select
CHRNA4 / NACHR Rabbit anti-Mouse Polyclonal (aa32-249) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$497; 200 µl/$632; 500 µl/$1,132; 1 ml/$1,369; 2 ml/$1,916; 5 ml/$3,592
CHRNA4 / NACHR Antibody - Western blot of CHRNA4 / NACHR antibody.
Select
CHRNA4 / NACHR Rabbit anti-Mouse Polyclonal (aa32-249) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
CHRNA4 / NACHR Antibody - Western blot of CHRNA4 / NACHR antibody.
Select
CHRNA4 / NACHR Rabbit anti-Mouse Polyclonal (aa32-249) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
5 ml/$694
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal (aa1-451) Antibody
Human
WB
Unconjugated
100 µg/$749
CHRNA4 / NACHR Antibody - CHRNA4 antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CHRNA4 / NACHR Antibody - CHRNA4 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
WB
Unconjugated
100 µl/$424
CHRNA4 / NACHR Antibody
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
CHRNA4 / NACHR Antibody - Western blot analysis of extracts of mouse kidney, using CHRNA4 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal Antibody
Mouse
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CHRNA4 / NACHR Antibody - Western blot of CHRNA4 / NACHR antibody.
Select
CHRNA4 / NACHR Rabbit anti-Human Polyclonal (aa49-242) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
Viewing 1-25 of 59 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).