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CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

Gene Name: cholinergic receptor, nicotinic, alpha 3 (neuronal)
Family/Subfamily: Ion Channel , Nicotinic acetylcholine receptor
Synonyms: CHRNA3, AChR-alpha3, Acra-3, LNCR2, NAChR alpha 3, PAOD2, NACHRA3
Target Sequences: NM_000743 NP_000734.2 P32297

Publications (1)

1
Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk. Falvella FS, Galvan A, Frullanti E, Spinola M, Calabr E, Carbone A, Incarbone M, Santambrogio L, Pastorino U, Dragani TA. Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 15:1837-42. (IHC-P; Human) [PubMed:19223495] Related Antibodies: LS-B934.

☰ Filters
Antibodies (40)
Proteins (5)
ELISA Kits (1)
Primary (40)
Recombinant (5)
Sandwich (1)
CHRNA3 (46)
Human (41)
Mouse (22)
Rat (15)
Bovine (7)
Chicken (1)
Dog (6)
Gibbon (6)
Guinea pig (3)
Horse (6)
Monkey (7)
Pig (3)
Rabbit (6)
IHC (21)
IHC-Fr (1)
IHC-P (9)
WB (38)
Flo (5)
ELISA (12)
ICC (4)
Peptide-ELISA (2)
rabbit (39)
mouse (1)
Product Group
IHCPlus (2)
IgG (17)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (39)
6D3A10 (1)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (20)
aa32-240 (8)
aa25-52 (7)
aa26-75 (4)
aa35-84 (4)
C-Terminus (3)
Internal (2)
Leu139 (1)
aa90-139 (1)
No (45)
Yes (1)
Tissue Homogenates (1)
10His-SUMO, N-terminus + Myc, C-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (1)
Human (5)
E. coli (3)
Wheat Germ Extract (2)
Purified (3)
CHRNA3 Antibody - Anti-CHRNA3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNA3 Rabbit anti-Human Polyclonal (aa26-75) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CHRNA3 Antibody - Anti-CHRNA3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNA3 Rabbit anti-Human Polyclonal (aa26-75) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CHRNA3 Antibody - Anti-CHRNA3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNA3 Rabbit anti-Human Polyclonal (aa26-75) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CHRNA3 Antibody - Anti-CHRNA3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNA3 Rabbit anti-Human Polyclonal (aa26-75) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CHRNA3 Antibody - Immunofluorescence analysis of SMMC-7721 cells using CHRNA3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher
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CHRNA3 Mouse anti-Human Monoclonal (6D3A10) Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µl/$459
CHRNA3 Antibody - Anti-CHRNA3 antibody IHC of human colon-myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNA3 Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CHRNA3 Antibody - Anti-CHRNA3 antibody IHC of human colon-myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNA3 Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CHRNA3 Antibody - Anti-CHRNA3 antibody IHC of human colon-myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CHRNA3 Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CHRNA3 Antibody - Anti-CHRNA3 antibody IHC of human colon-myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNA3 Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CHRNA3 Antibody - CHRNA3 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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CHRNA3 Rabbit anti-Human Polyclonal (aa25-52) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CHRNA3 Antibody - Western blot analysis of CHRNA3 using anti-CHRNA3 antibody
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CHRNA3 Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
10 µg/$318; 100 µg/$470
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CHRNA3 Rabbit anti-Human Polyclonal (aa25-52) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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CHRNA3 Rabbit anti-Human Polyclonal (aa25-52) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
CHRNA3 Rabbit anti-Human Polyclonal (aa25-52) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
CHRNA3 Rabbit anti-Human Polyclonal (aa25-52) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
CHRNA3 Rabbit anti-Human Polyclonal (aa25-52) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
CHRNA3 Rabbit anti-Human Polyclonal (aa25-52) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
CHRNA3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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CHRNA3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
CHRNA3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$587
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CHRNA3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$717
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CHRNA3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
CHRNA3 Antibody - Western blot analysis of extracts of various cell lines, using CHRNA3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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CHRNA3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CHRNA3 Antibody - Western blot testing of human 1) HeLa, 2) MDA-MB-453, 3) Jurkat, 4) HepG2, 5) SK-OV-3, 6) PANC-1 and 7) mouse thymus lysate with CHRNA3 antibody at 0.5ug/ml. Predicted molecular weight ~57 kDa.
Select
CHRNA3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, WB
Unconjugated
100 µg/$575
CHRNA3 Antibody - Western blot of AChRalpha3 antibody
Select
CHRNA3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Viewing 1-25 of 46 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).