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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CHRM4 / M4 Antibody LS‑C9137
Antibody
M4 antibody LS-C9137 is an unconjugated mouse monoclonal antibody to M4 (CHRM4) from human, rat and monkey. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C9137-100
100 µl (1 mg/ml)
Unavailable

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Product Description

M4 antibody LS-C9137 is an unconjugated mouse monoclonal antibody to M4 (CHRM4) from human, rat and monkey. Validated for IHC, IP and WB.
About CHRM4 / M4
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. P08173 NM_000741 NP_000732.2

CHRM4 Antibody, M4 muscarinic receptor Antibody, M4R Antibody, Muscarinic m4 receptor Antibody, HM4 Antibody, Muscarinic receptor m4 Antibody


Specifications

Target
Human CHRM4 / M4
Host
Mouse
Reactivity
Human, Monkey, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CHRM4 / M4 antibody was raised against m4 receptor i3 loop (human), fused to GST.
Specificity
Recognizes human M4 muscarinic acetylcholine receptor. No reactivity with the other subtypes. Species cross-reactivity: rat and monkey.
Usage
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Western Blot: Transfected CHO cell lines.
Presentation
PBS, 0.09% sodium azide.
Storage
Short term: 4°C, Long term: aliquot to Avoid freeze-thaw cycles, and store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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