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Anti-CHRM4 / M4 Antibody (aa469-478) LS-C9139

Catalog Size Price
LS-C9139-100 100 µl Unavailable
LS-C9139-500 500 µl Unavailable

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Rabbit Polyclonal (IgG) to Human CHRM4 / M4
IHC, Western blot, ELISA


Human CHRM4 / M4
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Ammonium sulfate precipitation


  • IHC (50 µg/ml)
  • Western blot

Specificity and Use

CHRM4 / M4 antibody was raised against peptide analogue of the carboxyl terminal of the M4 receptor covalently attached onto a carrier protein.
Shown to be specific for the COOH terminal of the M4 receptor. Cross-reactivity: M4 Muscarinic Receptor (aa469-478): 100%, M4 Muscarinic Receptor: ~70%. No reactivity is observed with M1-M3, M5 (full receptors), M1 (aa451-460), M2 (aa457-466), M3 Muscarinic Receptor (aa580-589), M5 (aa519-531).
Suitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications have been tested. Immunohistochemistry: 50 ug/ml stains PLP fixed cultured cells known to express the Muscarinic Receptor M4.


PBS, pH 7.2, 10 mg/ml BSA, 40% glycerol.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About CHRM4 / M4

P08173 NM_000741 NP_000732.2

CHRM4 Antibody, M4 muscarinic receptor Antibody, M4R Antibody, Muscarinic m4 receptor Antibody, HM4 Antibody, Muscarinic receptor m4 Antibody

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system.

Requested From: 
Date Requested: 5/20/2018

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