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Anti-CHRM3 / M3 Antibody (aa580-589) LS-C9135

Note: This antibody replaces LS-C37396

Ordering

Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $770
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Rabbit Polyclonal (IgG) to Human CHRM3 / M3
Human, Rat
IHC, Western blot, ELISA
Unconjugated

Details

Human CHRM3 / M3
Rabbit
Human, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Purified

Applications

IHC, Western blot, ELISA

Specificity and Use

CHRM3 / M3 antibody was raised against a peptide analogue of the carboxyl terminal of the M3 receptor covalently attached to a carrier protein.
aa580-589
Recognizes rat M3 Muscarinic Receptor (aa580-589): 100%; M3 Muscarinic Receptor 70%; M1 Muscarinic Receptor (aa451-460) 0%; M1 Muscarinic Receptor 0%; M2 Muscarinic Receptor (aa457-466) 0%; M2 Muscarinic Receptor 0%; M4 Muscarinic Receptor (aa469-478) 0%; M4 Muscarinic Receptor 0%; M5 Muscarinic Receptor (aa419-531) 0%; M5 Muscarinic Receptor 0%. This antibody is also specific for the COOH terminal of the M3 receptor as characterized by Western Blot, ELISA and IHC.
Suitable for use in ELISA, Immunohistochemistry and Western Blot. Immunohistochemistry: 10 ug/ml had been found to stain rat brain sections that express the muscarinic M3 receptor after fixing with PLP fixative and using ABC techniques. Western Blot: homogenates whole rat brain.

Packaging

PBS, 10 mg/ml BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CHRM3 / M3

P20309 NM_000740 NP_000731.1

CHRM3 Antibody, M3 Antibody, Muscarinic receptor M3 Antibody, Muscarinic M3 receptor Antibody, EGBRS Antibody, HM3 Antibody, M3 muscarinic receptor Antibody

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system.

Requested From: United States
Date Requested: 9/25/2016

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