Bacteria Cholera Toxin

Rabbit

Bacteria (tested or 100% immunogen sequence identity)

IgG Polyclonal

Horseradish Peroxidase

Purified

Unmodified

Purified Choleragenoid.

Recognizes the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

• Western blot (1:20 - 1:200)
• ELISA (1:200 - 1:1000)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS, 0.002% Thimerosal, 1% BSA

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.