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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CHGA / Chromogranin A Antibody LS‑C152927
Antibody
Chromogranin A antibody LS-C152927 is an unconjugated mouse monoclonal antibody to Chromogranin A (CHGA) from human and monkey. Validated for IHC and WB.
Catalog
Size
Price
LS-C152927-100
100 µg (1 mg/ml)
Unavailable

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Product Description

Chromogranin A antibody LS-C152927 is an unconjugated mouse monoclonal antibody to Chromogranin A (CHGA) from human and monkey. Validated for IHC and WB.
About CHGA / Chromogranin A
CHGA / Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. P10645 NM_001275 NP_001266.1

CHGA Antibody, Chromogranin A Antibody, Chromogranin-A Antibody, Pancreastatin Antibody, Pituitary secretory protein I Antibody, Vasostatin I Antibody, SP-I Antibody, Vasostatin II Antibody


Specifications

Target
Human CHGA / Chromogranin A
Host
Mouse
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:500 - 1:2000)
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human pheochromocytoma
Specificity
Chromogranin A. The antibody has been extensively documented on immunohistochemical studies in deparaffinized methacarn fixed tissue, where it is a sensitive marker of neuroendocrine cells and tumors. Not recommended for formalin fixed tissues, see MAB5268 or CBL219. On western blots, it identifies the identical bands recognized by antibody LK2H10 (Wilson and Lloyd)
Usage
Immunohistochemistry: 1:500-1:2000 on alcohol fixed deparaffinized tissue sections (ABC peroxidase) or 1:10000 on Methacarn-fixed deparaffinized tissue sections. Will show fine granular cytoplasmic staining associated with secretory granules. Western Blot
Presentation
0.02 M phosphate buffer, pH 7.6, 0.25 M sodium chloride, 0.1% sodium azide
Storage
4°C. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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