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Anti-CHEK1 / CHK1 Antibody (Ser280) IHC-plus™ LS-B1466

Note: This antibody replaces LS-C34339, LS-C79123, LS-C51487, LS-C118074


Wt. Vol. Conc. Price
50 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CHEK1 / CHK1 Antibodies

Anti-CHEK1 / CHK1 Antibody (aa192-241) IHC-plus™ LS-B932
Rabbit Polyclonal to Human CHEK1 / CHK1
Human, Monkey, Mouse, Rat, Bat, Dog, Horse, Rabbit, Zebrafish
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-CHEK1 / CHK1 Antibody LS-C43054
Goat Polyclonal (IgG) to Human CHEK1 / CHK1
Western blot, Immunoprecipitation
Western blot Image
Anti-CHEK1 / CHK1 Antibody (phospho-Ser345) LS-C177888
Rabbit Polyclonal to Human CHEK1 / CHK1
Human, Mouse, Rat
IHC - Paraffin
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human CHEK1 / CHK1
IHC - Paraffin, Western blot


Human CHEK1 / CHK1
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:500 - 1:1000)

Specificity and Use

CHEK1 / CHK1 antibody was raised against synthetic peptide from human CHEK1 / CHK1.
Amino acids surrounding Ser 280 of human CHK1
Immunohistochemistry: LS-B1466 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1466 was determined to be 10 ug/ml.


PBS, 0.02% sodium azide, 50% glycerol.
Long term: -70°C; Short term: -20°C
For research use only.

About CHEK1 / CHK1

O14757 NM_001274 NP_001265.2

CHEK1 Antibody, CHK1 checkpoint homolog Antibody, Cell cycle checkpoint kinase Antibody, Checkpoint kinase 1 Antibody, CHK1 Antibody, Chk1-S Antibody, Protein kinase chk1 Antibody, Checkpoint kinase-1 Antibody

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. This regulation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C.


Anti-Chk1 antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1466 concentration 10 ug/ml.

Requested From: United States
Date Requested: 10/26/2016

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