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Anti-CHEK1 / CHK1 Antibody (aa251-300) LS-C109689

Ordering

Wt. Vol. Conc. Price
50 µg - - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CHEK1 / CHK1 Antibodies

Anti-CHEK1 / CHK1 Antibody (aa192-241) IHC-plus™ LS-B932
Rabbit Polyclonal to Human CHEK1 / CHK1
Human, Monkey, Mouse, Rat, Bat, Dog, Horse, Rabbit, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CHEK1 / CHK1 Antibody LS-C43054
Goat Polyclonal (IgG) to Human CHEK1 / CHK1
Human
Western blot, Immunoprecipitation
Unconjugated
Western blot Image
Anti-CHEK1 / CHK1 Antibody (phospho-Ser345) LS-C177888
Rabbit Polyclonal to Human CHEK1 / CHK1
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human CHEK1 / CHK1
Human, Monkey, Mouse, Rat, Bat, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human CHEK1 / CHK1
Rabbit
Human, Monkey, Mouse, Rat, Bat, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Bovine, Xenopus (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

CHEK1 / CHK1 antibody was raised against synthetic peptide located between aa251-300 of human CHEK1 (O14757, NP_001265). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Rabbit, Horse, Pig, Guinea pig, Chicken (100%); Bovine, Platypus (92%); Zebra finch, Xenopus (91%); Opossum (85%).
LS-E11439 - Lyophilized - 100 µg - $145.00
aa251-300
Human CHEK1 / CHK1
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CHEK1 / CHK1

O14757 NM_001274 NP_001265.2

CHEK1 Antibody, CHK1 checkpoint homolog Antibody, Cell cycle checkpoint kinase Antibody, Checkpoint kinase 1 Antibody, CHK1 Antibody, Chk1-S Antibody, Protein kinase chk1 Antibody, Checkpoint kinase-1 Antibody

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. This regulation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C.

Western blot

Western blot
CHEK1 / CHK1 antibody LS-C109689 Western blot of Fetal Small Intestine lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/9/2016

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