Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation
IHC - Frozen (1:200 - 1:800)
Specificity and Use
CGA / hCG Alpha antibody was raised against purified human TSH alpha.
Polyclonal antibody is specific for the alpha subunit of human thyroid stimulating hormone (TSH). It cross reacts with the alpha subunit of human chorionic gonadotrophin and exhibits 30% reactivity with intact TSH. Antibody shows little or no cross-reactivity with other major human intact glycoprotein hormones including follicle stimulating hormone, growth hormone or prolactin. The antibody does not react with the beta chain of any of the glycoprotein hormones studied by radio-immune assay.
Lyophilized, 0.05 M ammonium bicarbonate.
50 µl Distilled Water. For long term storage, addition of a preservative is recommended.
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.