Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone OX-24] (IgG1) to Human CFH / Complement Factor H
Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Human CFH / Complement Factor H
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [OX-24]
IHC - Paraffin
Specificity and Use
CFH / Complement Factor H antibody was raised against human complement factor H.
Anti-human factor H (beta 1H) (139 kD) monoclonal antibody clone OX-24 inhibits the binding of factor H to surface bound C3. This antibody recognizes the human serum complement protein factor H and a 43-49kD truncated form of factor H present at low leve.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.1% sodium azide, EIA grade BSA.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
CFH Antibody, Adrenomedullin binding protein Antibody, AHUS1 Antibody, AMBP1 Antibody, ARMS1 Antibody, ARMD4 Antibody, Beta-1-H-globulin Antibody, Factor H Antibody, Factor H-like 1 Antibody, HF Antibody, HF2 Antibody, H factor 1 Antibody, H factor 2 (complement) Antibody, HUS Antibody, HF1 Antibody, Beta-1H Antibody, CFHL3 Antibody, Complement factor H Antibody, H factor 1 (complement) Antibody
CFH / Complement Factor H is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy.