Human CFB / Complement Factor B

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

10-09

Unconjugated

Protein A purified

Unmodified

Human factor B.

N-Terminus

Recognizes the Bb fragment of 90 kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kD Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation. Binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.

• IHC - Frozen
• Western blot
• Flow Cytometry
• ELISA

ELISA: LS-C44981 binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.

BBS, 0.1% Sodium Azide

Before reconstitution store at 4°C. After reconstitution store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P00751 NCBI: NM_001710 NP_001701.2