CFB / Complement Factor B

complement factor B

CFB / Complement Factor B is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

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Products

Antibodies (144)

ELISA Kits (26)

Proteins (19)

Type

Competitive EIA (1)

Custom (3)

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (2)

Primary (144)

Recombinant (16)

Sandwich (22)

Target

CFB / Complement Factor B (189)

Reactivity

Human (97)

Mouse (52)

Rat (53)

Bovine (1)

Chicken (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Rhesus monkey (1)

Application

IHC (29)

IHC-Fr (4)

IHC-P (12)

WB (133)

Flo (18)

ELISA (41)

Func (1)

ICC (10)

ID (2)

IF (2)

IP (8)

Peptide-ELISA (2)

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Host

rabbit (106)

mouse (35)

goat (3)

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IHCPlus (5)

Isotype

IgG (35)

IgG1 (15)

IgG1 + IgG2b (1)

IgG2a (6)

IgG2b (3)

Clonality

monoclonal mc (35)

polyclonal pc (109)

Clone

014III-33.2.4.3 (1)

032B-22.1.X (1)

10-09 (1)

KT21 (1)

KT24 (1)

Format

96-Well Microplate (3)

96-Well Strip Plate (23)

APC (10)

APC Conjugated (11)

Azide-free (1)

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Cy3 Conjugated (10)

Cy7 Conjugated (10)

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Epitope

aa270-388 (18)

aa34-159 (18)

aa35-160 (10)

aa269-382 (8)

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aa474-590 (8)

aa476-592 (8)

aa477-600 (8)

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N-Terminus (2)

210-290 aa, Internal (1)

Cleaved-Lys260 (1)

Internal (1)

aa23-761 (1)

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aa26-764 (1)

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Publications

No (189)

Sample Type

Cell Supernatant (1)

Plasma (21)

Serum (21)

Tissue Homogenates (4)

Tag

6His, C-terminus (2)

6His, N-terminus (1)

His (9)

His, N-Terminal (1)

His-GST (2)

His-MBP (1)

Myc-DDK (Flag) (3)

Species

Human (11)

Mouse (3)

Rat (4)

Source

293T Cells (1)

E. coli (13)

HEK 293 Cells (3)

Human Cells (1)

Mammalian Cells (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (3)

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IHC-plus™ CFB / Complement Factor B Antibody LS-B7934

(4.0) Rating

Antibody:

CFB / Complement Factor B Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ID, IHC, IHC-P

Format:

Unconjugated

Price:

1 ml/$485

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IHC-plus™ CFB / Complement Factor B Antibody (aa23-761) LS-B13829

(4.0) Rating

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa23-761) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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CFB / Complement Factor B Antibody (HRP) LS-C318647

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP

• Unconjugated
• HRP

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CFB / Complement Factor B Antibody (aa474-590) LS-C294091

Antibody:

CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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CFB / Complement Factor B Antibody (aa474-590, Biotin) LS-C299905

Antibody:

CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) (Biotin) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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CFB / Complement Factor B Antibody (aa32-157) LS-C294087

Antibody:

CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa32-157) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571

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CFB / Complement Factor B Antibody LS-C331647

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Monkey CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F42697

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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Mouse CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F20752

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse CFB / Complement Factor B Protein (Recombinant 6His, N-terminus) (aa23-761) - LS-G20601

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

86.9 kD

Price:

100 µg/$500; 1 mg/$1,679; 20 µg/$364

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Pig CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F19036

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F34565

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Human CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F5282

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$834

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Mouse CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F5963

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.39 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$854

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Rat CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F5964

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$893

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CFB / Complement Factor B Antibody (aa241-290) LS-C121072

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa241-290) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Human CFB / Complement Factor B Protein (Recombinant 6His, C-terminus) (Thr26-Leu764) - LS-G38857

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.07kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Rat CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F34566

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Mouse CFB / Complement Factor B (Competitive EIA) ELISA Kit - LS-F28259

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

25 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Rabbit CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F42698

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

31.25 - 2000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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CFB / Complement Factor B Antibody (N-Terminus, clone 014III-33.2.4.3) LS-C44996

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal (N-Terminus) (014III-33.2.4.3) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

0.1 ml/$568

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CFB / Complement Factor B Antibody (FITC) LS-C535147

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

100 µl/$1,063

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Rhesus monkey CFB / Complement Factor B (Sandwich ELISA) ELISA Kit - LS-F55381

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rhesus monkey

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$1,023

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Human CFB / Complement Factor B Protein (Recombinant His) (aa270-388) - LS-G14624

Source:

E. coli

Tag:

His

Molecular Weight:

14.9 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Rat CFB / Complement Factor B Protein (Recombinant His-MBP) (aa34-159) - LS-G14639

Source:

E. coli

Tag:

His-MBP

Molecular Weight:

60.9 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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