Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Overexpression of centromere protein K (CENP-K) gene in hepatocellular carcinoma promote cell proliferation by activating AKT/TP53 signal pathway. Wang H, Liu W, Liu L, Wu C, Wu W, Zheng J, Zhang M, Chen X, Zhou B, Gao Z, Huang J. Oncotarget. 2017 8:73994-74005. (WB; Human)[Full Text Article]
CENPK Antibody, Centromere protein K Antibody, CEMPK Antibody, AF5alpha Antibody, ICEN37 Antibody, p33 Antibody, Protein AF-5alpha Antibody, Leucine zipper protein FKSG14 Antibody, Solt Antibody, CENP-K Antibody, FKSG14 Antibody
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore.