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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CEA / Carcinoembryonic Antigen Antibody LS‑C12426
Carcinoembryonic Antigen antibody LS-C12426 is an unconjugated mouse monoclonal antibody to human Carcinoembryonic Antigen (CEA). Validated for IHC.
Antibody
Catalog
Size
Price
LS-C12426-1000
1000 µl
$605

Popular CEA / Carcinoembryonic Antigen Products

Formalin-fixed, paraffin-embedded human colon carcinoma stained with peroxidase-conjugate and DAB chromogen. Note cytoplasmic and luminal surface staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Anti-CEACAM5 / CEA antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7852 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA

Product Description

Carcinoembryonic Antigen antibody LS-C12426 is an unconjugated mouse monoclonal antibody to human Carcinoembryonic Antigen (CEA). Validated for IHC.

Specifications

Target
Human CEA / Carcinoembryonic Antigen
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen (1:10 - 1:40)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Purified CEA.
Specificity
CEA is a glycoprotein constituent of embryonic endodermal epithelium. It is a complex molecule of 200kD. Specific for CEA, 85 A12 may be used in studying and monitoring primary and secondary tumors of the gastrointestinal tract. Strongly stains tumor cells present in cancerous colon tissue. Only very weak staining of normal tissue observed. Does not cross-react with NCA (Non-specific cross-reacting antigen), another member of the CEA family.
Usage
Immunohistochemistry: (frozen)- 1:10-1:40, (paraffin)- 1:10-1:40. Positive control: Colon Adenocarcinoma.
Presentation
PBS, pH 7.2, 0.1% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CEA / Carcinoembryonic Antigen
Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore CEA is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical tests. Serum levels can also be elevated in heavy smokers.

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Requested From: United States
Date Requested: 10/16/2018

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