Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone PARLAM4] (IgG1) to Human CEA / Carcinoembryonic Antigen
IHC - Paraffin, IHC - Frozen
Human CEA / Carcinoembryonic Antigen
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [PARLAM4]
IHC - Paraffin (1:5 - 1:10)
IHC - Frozen (1:5 - 1:10)
Specificity and Use
Human carcinoembryonic antigen (CEA) from the membrane of human colon carcinoma cells.
Recognizes human carcinoembryonic antigen (CEA). Does not react with granulocytes, bile canaliculi or alveolar epithelium. Does not cross react with BGP or NCA.
Suitable for use in Immunohistochemistry. Immunohistochemistry (Frozen, paraffin): 1:5-1:10 using the Indirect method. Fix frozen sections with acetone for 5 min. at -20C. Pretreatment not required for paraffin sections.
Tris/HCl, 0.09% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months
For research use only.
About CEA / Carcinoembryonic Antigen
Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore CEA is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical tests. Serum levels can also be elevated in heavy smokers.